Jie Nue Qi Bao Yin

Seven Treasures Drink to Check Malarial Disorders · 截瘧七寶飲

Also known as: Qi Bao Yin (七宝饮), Qi Bao San (七宝散), Qi Bao Tang (七宝汤)

A classical anti-malarial formula designed to break the cycle of alternating chills and fever caused by turbid Phlegm and Dampness lodged in the body. It combines strong Phlegm-expelling and Dampness-drying herbs with Qi-moving ingredients to interrupt recurrent malarial attacks. Best suited for people with a robust constitution who experience repeated bouts of malaria with a greasy tongue coating.

Origin Yang Shi Jia Cang Fang (杨氏家藏方, Yang Family Stored Formulas) by Yang Tan — Southern Sòng dynasty, 1178 CE
Composition 7 herbs
Chang Shan
King
Chang Shan
Cao Guo
Deputy
Cao Guo
Bing Lang
Deputy
Bing Lang
Hou Pu
Assistant
Hou Pu
Qing Pi
Assistant
Qing Pi
Chen Pi
Assistant
Chen Pi
Gan Cao
Envoy
Gan Cao
Explore composition

Educational content Consult qualified TCM practitioners for diagnosis and treatment

Patterns Addressed

In TCM, symptoms don't appear randomly — they cluster into recognizable patterns of disharmony that reveal what's out of balance in the body. Jie Nue Qi Bao Yin is designed to correct these specific patterns.

Why Jie Nue Qi Bao Yin addresses this pattern

When turbid Phlegm and Dampness accumulate in the middle burner and lodge in the space between the interior and exterior (the membrane source), they provide a foothold for the malarial pathogen. The Spleen's failure to transform and transport fluids leads to the generation of Phlegm, which then obstructs Qi circulation. This obstruction causes the characteristic alternating chills and fever as the body's Qi struggles to push the pathogen out. Jie Nue Qi Bao Yin addresses this pattern with Chang Shan as the chief anti-malarial agent that expels old Phlegm, supported by Cao Guo and Bing Lang that powerfully dry Dampness and break up Phlegm accumulation, while Hou Po, Qing Pi, and Chen Pi restore Qi flow in the middle burner and prevent further Phlegm generation.

A practitioner would look for one or more of these signs

Chills

Regular, timed attacks that recur daily or every other day

Thick White Tongue Coating

White, greasy tongue coating indicating Phlegm-Dampness

Nausea

Nausea and chest stuffiness from turbid Phlegm blocking the middle burner

Eye Fatigue

Yawning and fatigue before the onset of an attack

Excessive Sweating

Profuse sweating at the end of each attack

Headaches

Headache during the heat phase of the attack

Thirst

Thirst and flushed face during fever

Commonly Prescribed For

These conditions can arise from the patterns above. A practitioner would consider Jie Nue Qi Bao Yin when these conditions are specifically caused by those patterns — not for all cases of these conditions.

Arises from: Phlegm-Dampness in the Middle-Burner Shaoyang Pattern (Lesser Yang)

TCM Interpretation

In TCM, malaria is understood as a condition where an external pathogenic factor (called the 'malarial pathogen' or nue xie) penetrates into the space between the body's interior and exterior, a region sometimes described as the 'membrane source' (mo yuan). When it lodges here, it disrupts the normal flow of Qi between the Yin (interior) and Yang (exterior) aspects of the body. When the pathogen struggles with the body's protective Qi in the exterior, fever results. When it retreats inward, chills dominate. This tug-of-war produces the characteristic cyclical pattern of alternating chills and fever. The Spleen plays a central role because when it fails to properly transform fluids, Phlegm and Dampness accumulate, creating the ideal environment for the pathogen to take hold. People with pre-existing Phlegm-Dampness or weak Spleen function are particularly vulnerable.

Why Jie Nue Qi Bao Yin Helps

Jie Nue Qi Bao Yin directly targets both the malarial pathogen and its enabling environment. Chang Shan is the principal anti-malarial agent whose active alkaloids (confirmed by modern pharmacological research) directly combat the malarial pathogen while expelling old Phlegm. Cao Guo and Bing Lang form a classical anti-malarial pair: Cao Guo dries the Dampness in which the pathogen shelters, while Bing Lang drives Qi downward to dislodge the pathogen from the membrane source. The three aromatic assistants (Hou Po, Qing Pi, Chen Pi) work together to restore normal Qi circulation in the middle burner, preventing the re-accumulation of turbid Phlegm. The wine in the preparation method helps carry the herbs' action to the half-exterior, half-interior level where the pathogen resides. This formula is best suited for robust patients with clear signs of Phlegm-Dampness (greasy tongue coating, slippery pulse) and should not be used in people who are weak or deficient.

Also commonly used for

Fever

Cyclical fevers with regular periodicity, especially with Phlegm-Dampness signs

Influenza

When presenting with alternating chills and fever and a greasy tongue coating

What This Formula Does

Every TCM formula has a specific set of actions — here's what Jie Nue Qi Bao Yin does in the body, explained in both everyday and TCM terms

Therapeutic focus

In practical terms, Jie Nue Qi Bao Yin is primarily used to support these areas of health:

TCM Actions

In TCM terminology, these are the specific therapeutic actions that Jie Nue Qi Bao Yin performs to restore balance in the body:

How It Addresses the Root Cause

TCM doesn't just suppress symptoms — it aims to resolve the underlying imbalance. Here's how Jie Nue Qi Bao Yin works at the root level.

In TCM theory, malaria (疟疾, nüè jí) arises when a malarial pathogen lodges between the body's Yin and Yang layers, causing alternating episodes of chills and fever as the pathogen shifts back and forth. Specifically, when the pathogen enters the half-exterior, half-interior level (the Shaoyang domain), the body's defensive Qi and the pathogen clash at regular intervals, producing the characteristic pattern of shaking chills followed by high fever, then sweating and relief, repeating in a cyclical rhythm.

This formula targets the particular scenario where Phlegm and Dampness are a major complicating factor. When the Spleen is burdened by rich or greasy foods, or when constitutional Dampness is already present, turbid fluids congeal into Phlegm that accumulates in the middle burner (the digestive center). This Phlegm obstructs the free flow of Qi, providing a kind of "nest" in which the malarial pathogen can hide. The Qi becomes stagnant and knotted, the Spleen's ability to transform and transport is impaired, and the repeated malarial attacks become entrenched and difficult to stop. The tongue will typically show a thick, greasy, white coating, and the pulse will be wiry and slippery, reflecting both the Phlegm obstruction and the Shaoyang involvement.

Because the root problem is this combination of external malarial pathogen plus internal Phlegm-Dampness congestion, the treatment must simultaneously intercept the malaria (stopping the cyclical attacks directly) while powerfully drying Dampness, dissolving Phlegm, and moving the stagnant Qi in the middle burner. By clearing the Phlegm from the middle, the formula removes the pathogen's foothold, allowing the body to break free of the recurring cycle.

Formula Properties

Every formula has an inherent temperature, taste, and affinity for specific organs — these properties determine how it interacts with the body

Overall Temperature

Warm

Taste Profile

Predominantly bitter and pungent with some sweetness from Licorice. Bitter to drain Dampness and clear Phlegm, pungent to move Qi and open stagnation.

Ingredients

7 herbs

The herbs that make up Jie Nue Qi Bao Yin, organized by their role in the prescription

King — Main ingredient driving the formula
Deputy — Assists and enhances the King
Assistant — Supports or moderates other herbs
Envoy — Directs the formula to its target
King — Main ingredient driving the formula
Chang Shan

Chang Shan

Dichroa roots

Dosage 6 - 9g
Temperature Cold
Taste Bitter, Pungent
Organ Affinity Heart, Liver, Lungs
Preparation Stir-fried with wine (酒炒) to reduce nausea and direct the herb's action

Role in Jie Nue Qi Bao Yin

The primary anti-malarial herb that expels old Phlegm and accumulated fluid from the body, directly interrupting the malarial cycle. Its bitter and cold nature drives out the pathogenic factor responsible for recurrent attacks.
Deputies — Assists and enhances the King
Cao Guo

Cao Guo

Tsaoko fruits

Dosage 6 - 9g
Temperature Warm
Taste Pungent
Organ Affinity Spleen, Stomach
Preparation Roasted in its husk (煨) to moderate its harshness

Role in Jie Nue Qi Bao Yin

Powerfully dries Dampness and disperses Cold lodged in the Spleen, helping to dissolve the turbid Phlegm that sustains the malarial pattern. Its warm, aromatic nature complements Chang Shan's cold property.
Bing Lang

Bing Lang

Areca nuts

Dosage 6 - 9g
Temperature Warm
Taste Bitter, Pungent
Organ Affinity Large Intestine, Stomach

Role in Jie Nue Qi Bao Yin

Moves Qi downward and breaks up Phlegm accumulation, helping to dislodge pathogenic factors from the membrane source (膜原). Has a traditional reputation for treating miasmic disorders and malarial conditions.
Assistants — Supports or moderates other herbs
Hou Pu

Hou Pu

Houpu Magnolia bark

Dosage 6 - 9g
Temperature Warm
Taste Bitter, Pungent
Organ Affinity Lungs, Spleen, Stomach

Role in Jie Nue Qi Bao Yin

Moves Qi and dries Dampness in the middle burner, relieving distension and helping to dissolve turbid Phlegm that blocks the Spleen's normal function.
Qing Pi

Qing Pi

Green tangerine peel

Dosage 6 - 9g
Temperature Warm
Taste Bitter, Pungent
Organ Affinity Gallbladder, Stomach, Liver

Role in Jie Nue Qi Bao Yin

Breaks up stagnant Qi and disperses accumulations. Its bitter and warming nature helps drive out the pathogenic factor lodged between the interior and exterior.
Chen Pi

Chen Pi

Tangerine peel

Dosage 6 - 9g
Temperature Warm
Taste Bitter, Pungent
Organ Affinity Lungs, Spleen

Role in Jie Nue Qi Bao Yin

Regulates the Spleen and Stomach Qi, dries Dampness, and transforms Phlegm. Works with Qing Pi and Hou Po to restore normal Qi flow in the middle burner.
Envoy — Directs the formula to its target
Gan Cao

Gan Cao

Liquorice

Dosage 3 - 6g
Temperature Neutral
Taste Sweet
Organ Affinity Heart, Lungs, Spleen, Stomach

Role in Jie Nue Qi Bao Yin

Harmonizes the formula, tonifies the Spleen and Stomach to protect the middle burner from the drying and harsh nature of the other ingredients, and moderates potential toxicity.

Why This Combination Works

How the herbs in Jie Nue Qi Bao Yin complement each other

Overall strategy

This formula targets the pathomechanism of turbid Phlegm and Dampness obstructing the space between interior and exterior, which allows the malarial pathogen to lodge and cause recurrent attacks of alternating chills and fever. The prescription combines powerful Phlegm-expelling and malaria-interrupting herbs with aromatic Qi-moving agents that dry Dampness and restore the Spleen's transforming function.

King herbs

Chang Shan (Dichroa root) serves as the sole King herb. Classical sources describe it as a herb that enters the Shaoyang and Taiyin channels, able to expel old Phlegm and accumulated fluids. It directly interrupts the malarial cycle by dislodging the pathogenic factor from its lodging place. Wine processing reduces its tendency to cause nausea while enhancing its ability to reach the site of the disease.

Deputy herbs

Cao Guo Ren and Bing Lang form a classical pairing for treating malarial and miasmic conditions. Cao Guo's intensely warm and aromatic nature powerfully dries Dampness and disperses Cold in the Spleen (Taiyin), dissolving the turbid Phlegm that sustains the disease. Bing Lang descends Qi and breaks up Phlegm accumulation, helping to dislodge the pathogenic factor from the membrane source. Together they reinforce Chang Shan's anti-malarial action from different angles.

Assistant herbs

Hou Po, Qing Pi, and Chen Pi form a trio of aromatic, Qi-moving, Dampness-drying assistants. Hou Po (reinforcing assistant) moves Qi and breaks up turbidity in the middle burner. Qing Pi (reinforcing assistant) disperses Qi stagnation with its sharp, penetrating nature. Chen Pi (reinforcing assistant) gently regulates Spleen and Stomach Qi while drying residual Dampness and Phlegm. Together, these three ensure that the middle burner is opened and the turbid accumulation has no place to hide.

Envoy herbs

Zhi Gan Cao (honey-fried Licorice) harmonizes the entire formula and protects the Spleen and Stomach from the drying, harsh nature of the other six ingredients. Given that this formula consists entirely of aromatic, bitter, and drying herbs, this protective function is essential to prevent damage to the Stomach.

Notable synergies

The combination of Chang Shan, Cao Guo, and Bing Lang is the formula's core anti-malarial trio, each addressing a different aspect: Chang Shan expels Phlegm upward, Bing Lang drives it downward, and Cao Guo dries it from the center. The addition of wine in the preparation method enhances the herbs' ability to reach the channels and the half-exterior, half-interior space where the malarial pathogen hides.

How to Prepare

Traditional preparation instructions for Jie Nue Qi Bao Yin

Chop all herbs coarsely and combine as a single dose. Decoct with equal parts water and rice wine (approximately 250 ml water and 70 ml wine). Cook over a slow fire until reduced to about 60% of the original volume. Strain the liquid, cover with silk cloth, and leave overnight exposed to the open air (known as 'dew exposure'). The next morning, on the day the malarial episode is expected, drink the decoction cold on an empty stomach, then rest briefly. If chills predominate, increase the proportion of wine; if heat predominates, increase the proportion of water. Avoid hot tea for the rest of the day, and eat warm congee at midday.

Common Modifications

How practitioners adapt Jie Nue Qi Bao Yin for specific situations

Added
Cang Zhu

6-9g, to strongly dry Dampness and invigorate the Spleen

Ban Xia

6-9g, to dry Dampness and transform Phlegm

When Phlegm-Dampness is exceptionally heavy, adding Cang Zhu and Ban Xia reinforces the formula's Dampness-drying and Phlegm-resolving power, helping to clear the turbid obstruction from the middle burner more effectively.

Educational content — always consult a qualified healthcare provider or TCM practitioner before using any herbal formula.

Contraindications

Situations where Jie Nue Qi Bao Yin should not be used or requires extra caution

Avoid

Persons with a weak constitution, deficient middle Qi, or internal deficiency-Heat. The Yi Fang Ji Jie warns that in those who are Qi-deficient with internal depressed Fire, these warm-drying herbs will further deplete the body: 'the more you force, the more deficient it becomes' (愈劫愈虚).

Avoid

Patients presenting with a deep, thin, choppy, or feeble pulse (脉沉涩微细), which indicates a deficiency or Blood-level pattern rather than a robust excess condition with Phlegm-Dampness.

Avoid

Pregnancy. Chang Shan (Dichroa root) is classified as toxic and is listed as 'cautiously used' during pregnancy in the Chinese Pharmacopoeia. Its emetic and purgative properties pose clear risk to the fetus.

Caution

Malaria of the Blood level (阴疟/血分疟), where the pathogen has entered deeper and manifests with night-time attacks. The classical commentary notes that for Blood-level patterns, Blood-moving herbs such as Wu Ling Zhi and Tao Ren should be added instead.

Caution

Patients prone to nausea and vomiting. Chang Shan is a known emetic and can provoke severe vomiting, especially in those with sensitive stomachs or weak digestion.

Caution

Yin-deficiency or Blood-deficiency patterns. The entire formula is composed of warm, drying, Qi-moving herbs that can further damage Yin and Blood.

Special Populations

Important considerations for pregnancy, breastfeeding, and pediatric use

Pregnancy

Contraindicated in pregnancy. Chang Shan (Dichroa root), the principal herb, is classified as toxic and is listed as 'cautiously used' (慎用) during pregnancy in the Chinese Pharmacopoeia. It is a potent emetic with known toxicity from its alkaloids (febrifugine and isofebrifugine), which pose risks to fetal development. Bing Lang (Areca seed) also has downward-moving, purgative properties that are considered unsafe during pregnancy. Multiple commercial and clinical references explicitly state Chang Shan should not be used during pregnancy. This formula should be avoided entirely by pregnant women.

Breastfeeding

Not recommended during breastfeeding. Chang Shan (Dichroa root) is classified as toxic and contains alkaloids (febrifugine, isofebrifugine) that may transfer into breast milk. The safety of these compounds for nursing infants has not been established. Bing Lang (Areca seed) contains arecoline, a cholinergic alkaloid that could also pose risks to a nursing infant. If antimalarial treatment is needed during breastfeeding, safer alternatives should be sought under professional guidance.

Children

This formula requires extreme caution in children due to the toxicity of Chang Shan (Dichroa root) and the harsh, drying nature of the entire composition. Children are more susceptible to the emetic effects of Chang Shan and the purgative action of Bing Lang. If used at all in pediatric patients, dosages should be significantly reduced (typically one-third to one-half of adult doses depending on age and body weight), and it should only be administered under close supervision by a qualified practitioner. Not suitable for infants or young children. The formula is designed for robust constitutions with clear signs of Phlegm-Dampness excess and should never be used in children showing signs of Qi deficiency or poor appetite.

Drug Interactions

If you are taking pharmaceutical medications, be aware of these potential interactions with Jie Nue Qi Bao Yin

Gan Cao (Licorice): Honey-processed Licorice (Zhi Gan Cao) in this formula may interact with corticosteroids (additive mineralocorticoid effects causing fluid retention and hypokalemia), digoxin and cardiac glycosides (hypokalemia potentiates toxicity), antihypertensive medications (fluid retention can counteract blood pressure lowering), and diuretics (compounding potassium loss).

Bing Lang (Areca seed): Contains arecoline, a cholinergic compound that may interact with cholinergic or anticholinergic medications. It may also potentiate the effects of cholinesterase inhibitors used in conditions like myasthenia gravis or Alzheimer's disease.

Chang Shan (Dichroa root): Contains febrifugine and related alkaloids. While no specific pharmaceutical drug interactions are extensively documented, the herb's emetic properties and hepatic effects warrant caution when combined with other hepatotoxic drugs or antiemetic medications (which may mask signs of toxicity). Concurrent use with antimalarial pharmaceuticals (chloroquine, artemisinin derivatives) should be monitored by a professional due to potential additive or unpredictable effects.

Usage Guidance

Practical advice for getting the most out of Jie Nue Qi Bao Yin

Best time to take

2-3 hours before the expected onset of the malarial attack, on an empty stomach. Classically served cold after being left out overnight (露一宿,次早温服).

Typical duration

Short-term acute use only: typically 1-3 doses timed to malarial attacks, reassessed after each episode. Not for prolonged use.

Dietary advice

Avoid greasy, rich, and fatty foods (膏粱厚味) that generate Dampness and Phlegm, as these directly worsen the Phlegm-Dampness pattern this formula addresses. Cold and raw foods, dairy products, and sugary or sticky foods should also be minimized. Alcohol in small amounts is traditionally used in the preparation (the decoction is cooked with rice wine), but excessive alcohol intake should be avoided. Light, easily digestible foods such as congee with a small amount of ginger are preferred during treatment. The classical instructions specify that the formula should be taken on an empty stomach for best effect.

Jie Nue Qi Bao Yin originates from Yang Shi Jia Cang Fang (杨氏家藏方, Yang Family Stored Formulas) by Yang Tan Southern Sòng dynasty, 1178 CE

Classical Texts

Key passages from the classical Chinese medical texts that first described Jie Nue Qi Bao Yin and its clinical use

《医方集解》 (Yī Fāng Jí Jiě, Collection and Explanation of Medical Formulas):

Original: 「治实疟久发不止,寸口脉弦滑浮大者……不问鬼疟、食疟,并皆治之。」
Translation: "Treats robust malaria with repeated attacks that will not stop, where the cun-kou pulse is wiry, slippery, floating, and large... Whether it is ghost-malaria or food-malaria, this formula treats them all."

《医方集解》commentary on pathomechanism:

Original: 「此足少阳、太阴药也。常山能吐老痰积饮,槟榔能下食积痰结,草果能消太阴膏粱之痰。」
Translation: "This is a formula for the Foot Shaoyang and Foot Taiyin channels. Chang Shan can expel old Phlegm and accumulated fluids, Bing Lang can move down Food Stagnation and knotted Phlegm, and Cao Guo can dissolve the Phlegm of rich food from the Taiyin."

《玉机微义》 (Yù Jī Wēi Yì) as quoted in the Yi Fang Ji Jie:

Original: 「上方乃温脾燥烈之药,盖作脾寒治也……若中气虚弱,内有郁火之人,复用燥热,愈劫愈虚,咎将谁执。」
Translation: "The above formula consists of Spleen-warming and intensely drying herbs, and is in essence a treatment for Spleen-Cold... If a person has weak middle Qi and internal depressed Fire, adding more drying-hot herbs will only strip them further, and who then is to blame?"

Historical Context

How Jie Nue Qi Bao Yin evolved over the centuries — its origins, lineage, and place in the broader tradition of Chinese medicine

Jie Nue Qi Bao Yin originates from the Yang Shi Jia Cang Fang (杨氏家藏方, Yang Family Treasury of Formulas), compiled by Yang Tan (杨倓, courtesy name Zi Jing 子靖) during the Southern Song dynasty and first published in 1178 CE. Yang Tan was not primarily a physician but a high-ranking official who served as Secretary of the Privy Council (签书枢密院事). He collected over 1,100 proven prescriptions from his family's archives, including formulas passed down from his father Yang Cunzhong (杨存中), a famous military general. The book was one of three celebrated Southern Song formula collections that circulated together in the Jianghuai region, alongside Hong Zun's Hong Shi Ji Yan Fang and Hu Yuanzhi's Hu Shi Jing Yan Fang.

The formula also appears under the names Qi Bao San (七宝散) in the original Yang text and Qi Bao Tang (七宝汤) in the Yi Jian Fang (易简方). The name "Jie Nue Qi Bao Yin" (截疟七宝饮) specifically appears in Yu Tuan's Yi Xue Zheng Zhuan (医学正传, 1515). The Qing-dynasty physician Wang Ang provided an influential commentary on this formula in his Yi Fang Ji Jie (医方集解), classifying it as a Shaoyang-Taiyin formula and adding important cautions about its misuse in deficient patients. Chang Shan's antimalarial properties were among the earliest Chinese herbal actions to be validated by modern pharmacology, with its alkaloid febrifugine demonstrated to have potent antimalarial activity.