Qing Pi Tang

Clear the Spleen Decoction · 清脾湯

Also known as: Qing Pi Yin

A classical formula designed to treat recurring episodes of chills and fever (such as in malarial disorders) where Dampness and Phlegm have accumulated in the body alongside Heat. It works by harmonizing the body's defences, clearing Heat, drying Dampness, and transforming Phlegm, while also supporting the Spleen to prevent further accumulation.

Origin Jì Shēng Fāng (济生方, Formulas to Aid the Living) by Yán Yònghé (严用和) — Sòng dynasty, 1253 CE
Composition 9 herbs
Chai Hu
King
Chai Hu
Huang Qin
King
Huang Qin
Ban Xia
Deputy
Ban Xia
Hou Pu
Assistant
Hou Pu
Cao Guo
Assistant
Cao Guo
Qing Pi
Assistant
Qing Pi
Bai Zhu
Assistant
Bai Zhu
Fu Ling
Assistant
Fu Ling
+1
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Educational content Consult qualified TCM practitioners for diagnosis and treatment

Patterns Addressed

In TCM, symptoms don't appear randomly — they cluster into recognizable patterns of disharmony that reveal what's out of balance in the body. Qing Pi Tang is designed to correct these specific patterns.

Why Qing Pi Tang addresses this pattern

In malarial disorders, the pathogenic factor lodges in the Shaoyang (Lesser Yang) level, caught between the exterior and interior. This produces the hallmark alternating chills and fever, as the body's defensive Qi struggles with the pathogen at this halfway point. Qing Pi Tang addresses this through Chai Hu and Huang Qin, which harmonize the Shaoyang by venting the pathogen outward and clearing Heat inward. What distinguishes this formula from standard Shaoyang-resolving formulas like Xiao Chai Hu Tang is the addition of strong Dampness-drying and Phlegm-transforming herbs (Cao Guo, Hou Po, Ban Xia) that target the Damp-Phlegm complication, along with Spleen-supporting herbs (Bai Zhu, Fu Ling) that address the root weakness.

A practitioner would look for one or more of these signs

Chills

Regular episodes with predictable timing

Nausea

Nausea or vomiting accompanying fever episodes

Feeling Of Chest Oppression

Fullness and oppression in the chest and epigastrium

Bitter Taste In The Mouth

Bitter taste in the mouth

Loss Of Appetite

Reduced appetite with abdominal distension

Commonly Prescribed For

These conditions can arise from the patterns above. A practitioner would consider Qing Pi Tang when these conditions are specifically caused by those patterns — not for all cases of these conditions.

Arises from: Lesser Yang-stage disorder Spleen Deficiency with Dampness

TCM Interpretation

In TCM, malaria is understood as an external pathogenic factor (often called 'malarial Qi') that enters the body and becomes lodged between the exterior and interior at the Shaoyang level. The pathogen alternately struggles with the body's defensive Qi, producing the characteristic cycle of chills (when the pathogen dominates) and fever (when the defensive Qi fights back). In cases where the patient's Spleen is weak, Dampness accumulates internally and combines with the pathogen to produce Phlegm, creating a more complex and stubborn condition. The Dampness-Phlegm acts like a harbour for the pathogen, making it harder to expel and leading to prolonged or frequently recurring episodes. Symptoms include not only the cyclic fevers but also chest and abdominal fullness, nausea, poor appetite, and a thick greasy tongue coating.

Why Qing Pi Tang Helps

Qing Pi Tang is specifically designed for malarial conditions complicated by Damp-Phlegm. The Chai Hu and Huang Qin pair resolves the Shaoyang entrapment of the pathogen, while Cao Guo directly targets the malarial mechanism with its strong aromatic Dampness-dispersing action. Ban Xia and Hou Po transform Phlegm and move Qi to relieve the chest and abdominal symptoms. Meanwhile, Bai Zhu and Fu Ling strengthen the Spleen to eliminate the root source of Dampness, and Qing Pi breaks through Qi stagnation. This multi-layered approach addresses both the acute malarial pathogen and the underlying Spleen-Dampness environment that sustains it.

Also commonly used for

Nausea

Nausea associated with fever and Dampness

Chronic Fatigue Syndrome

Post-malarial fatigue with Spleen weakness

Abdominal Distention

Epigastric fullness with greasy tongue coating

Fever

Recurrent or intermittent febrile conditions

What This Formula Does

Every TCM formula has a specific set of actions — here's what Qing Pi Tang does in the body, explained in both everyday and TCM terms

Therapeutic focus

In practical terms, Qing Pi Tang is primarily used to support these areas of health:

TCM Actions

In TCM terminology, these are the specific therapeutic actions that Qing Pi Tang performs to restore balance in the body:

How It Addresses the Root Cause

TCM doesn't just suppress symptoms — it aims to resolve the underlying imbalance. Here's how Qing Pi Tang works at the root level.

Qing Pi Tang addresses a specific pattern where malarial pathogenic factors become entangled with internal Dampness and Phlegm, creating a complex blockage in the Shaoyang (Lesser Yang) level. In TCM theory, the Shaoyang occupies a pivotal position between the body's exterior and interior. When a pathogen lodges here, it produces the hallmark symptom of alternating chills and fever, because the body's defensive Qi and the pathogen are locked in a back-and-forth struggle, neither fully winning nor losing.

In this particular pattern, the Spleen's ability to transform fluids is weakened, leading to the accumulation of Dampness that condenses into Phlegm. This Damp-Phlegm further obstructs the smooth flow of Qi through the middle region (chest and abdomen), producing symptoms like chest stuffiness, nausea, a greasy tongue coating, and a sense of heaviness. The Dampness also provides a sticky medium that harbors the malarial pathogen, making it harder to expel. The Gallbladder's function of spreading its clear Qi is impaired, contributing to a bitter taste in the mouth and fullness in the flanks.

The disease logic, then, is twofold: the pathogen trapped in the Shaoyang pivot causes the cyclic fevers, while the internal Damp-Phlegm fuels and prolongs the disorder. Unless both the pathogen and the Dampness are addressed simultaneously, the condition tends to recur. This is why a simple Shaoyang-harmonizing approach alone would be insufficient, and why the formula must also strongly dry Dampness, transform Phlegm, and support the Spleen's fluid-processing function.

Formula Properties

Every formula has an inherent temperature, taste, and affinity for specific organs — these properties determine how it interacts with the body

Overall Temperature

Warm

Taste Profile

Predominantly bitter and pungent — bitter to clear Heat and dry Dampness, pungent to move Qi and disperse stagnation, with mild sweet notes from Bai Zhu, Fu Ling, and Gan Cao to support the Spleen.

Ingredients

9 herbs

The herbs that make up Qing Pi Tang, organized by their role in the prescription

King — Main ingredient driving the formula
Deputy — Assists and enhances the King
Assistant — Supports or moderates other herbs
Envoy — Directs the formula to its target
Kings — Main ingredient driving the formula
Chai Hu

Chai Hu

Bupleurum roots

Dosage 6 - 9g
Temperature Cool
Taste Bitter
Organ Affinity Gallbladder, Liver

Role in Qing Pi Tang

Harmonizes the Shaoyang (Lesser Yang) level, vents pathogens outward through the half-exterior half-interior layer, and reduces alternating fever and chills. As the primary herb addressing the core malarial mechanism of pathogens lodged between exterior and interior, it anchors the entire formula.
Huang Qin

Huang Qin

Baikal skullcap roots

Dosage 6 - 9g
Temperature Cold
Taste Bitter
Organ Affinity Gallbladder, Heart, Large Intestine, Lungs, Small Intestine, Spleen

Role in Qing Pi Tang

Clears Heat from the Shaoyang and the interior, complementing Chai Hu's outward-venting action with inward Heat-clearing. Together they form the classical pair for resolving Lesser Yang disorders. Huang Qin's bitter-cold quality targets the Heat component of the malarial pathogen.
Deputy — Assists and enhances the King
Ban Xia

Ban Xia

Crow-dipper rhizomes

Dosage 6 - 9g
Temperature Warm
Taste Pungent
Organ Affinity Lungs, Spleen, Stomach

Role in Qing Pi Tang

Dries Dampness, transforms Phlegm, harmonizes the Stomach, and descends rebellious Qi to stop nausea and vomiting. In malarial conditions complicated by Damp-Phlegm, Ban Xia directly addresses the accumulated pathological fluids.
Assistants — Supports or moderates other herbs
Hou Pu

Hou Pu

Houpu Magnolia bark

Dosage 6 - 9g
Temperature Warm
Taste Bitter, Pungent
Organ Affinity Lungs, Spleen, Stomach

Role in Qing Pi Tang

Moves Qi, eliminates fullness in the chest and abdomen, dries Dampness, and transforms Phlegm. Works alongside Ban Xia and Qing Pi to address the distension and epigastric oppression caused by accumulated Dampness.
Cao Guo

Cao Guo

Tsaoko fruits

Dosage 3 - 6g
Temperature Warm
Taste Pungent
Organ Affinity Spleen, Stomach
Preparation Dry-fried until yellow (炒黄)

Role in Qing Pi Tang

Strongly dries Dampness and disperses Cold, with a specific traditional action of interrupting malarial cycles. Its warm, aromatic nature penetrates turbid Dampness lodged in the Spleen and Stomach, targeting the root cause of recurring episodes.
Qing Pi

Qing Pi

Green tangerine peel

Dosage 3 - 6g
Temperature Warm
Taste Bitter, Pungent
Organ Affinity Gallbladder, Stomach, Liver

Role in Qing Pi Tang

Breaks through Qi stagnation, disperses accumulation, and smooths the flow of Liver Qi. Addresses the epigastric and flank fullness associated with constrained Qi and Damp-Phlegm obstruction in malarial disorders. Also the namesake herb of the formula.
Bai Zhu

Bai Zhu

Atractylodes rhizomes

Dosage 6 - 9g
Temperature Warm
Taste Bitter, Sweet
Organ Affinity Spleen, Stomach

Role in Qing Pi Tang

Strengthens the Spleen, augments Qi, and dries Dampness. Supports the Spleen's transforming and transporting function to eliminate the root source of Dampness and prevent further Phlegm accumulation.
Fu Ling

Fu Ling

Poria-cocos mushrooms

Dosage 6 - 9g
Temperature Neutral
Taste Sweet
Organ Affinity Heart, Kidneys, Lungs, Spleen

Role in Qing Pi Tang

Promotes water metabolism, drains Dampness through urination, and supports the Spleen. Works with Bai Zhu to address the underlying Spleen weakness that generates Dampness, and provides a downward drainage route for accumulated pathological fluids.
Envoy — Directs the formula to its target
Gan Cao

Gan Cao

Liquorice

Dosage 3 - 4.5g
Temperature Neutral
Taste Sweet
Organ Affinity Heart, Lungs, Spleen, Stomach

Role in Qing Pi Tang

Harmonizes the actions of all the other herbs in the formula, moderates the harsh or drying qualities of the Dampness-resolving and Qi-moving herbs, and supports the Spleen with its sweet flavour.

Why This Combination Works

How the herbs in Qing Pi Tang complement each other

Overall strategy

Qing Pi Tang addresses malarial disorders where the pathogen has become entangled with Dampness and Phlegm in the half-exterior, half-interior (Shaoyang) level. The formula simultaneously harmonizes the Shaoyang to expel the malarial pathogen, clears interior Heat, dries Dampness, transforms Phlegm, and strengthens the Spleen to cut off the source of further Dampness production.

King herbs

Chai Hu and Huang Qin form the core pair, modelled on the Xiao Chai Hu Tang (Minor Bupleurum Decoction) structure. Chai Hu vents the pathogen outward from the Shaoyang layer and lifts clear Yang, while Huang Qin clears Heat from the interior. Together, one ascending and one descending, one scattering and one draining, they resolve the alternating chills and fever that define the Lesser Yang pattern.

Deputy herbs

Ban Xia directly transforms the Phlegm-Dampness that complicates the malarial disorder. It also descends Stomach Qi to relieve the nausea and chest oppression commonly seen in these patients. Together with the King herbs, it echoes the core of Xiao Chai Hu Tang adapted for Dampness conditions.

Assistant herbs

Cao Guo (reinforcing assistant) is the specific anti-malarial herb, strongly drying Dampness and dispersing Cold from the middle burner. Hou Po (reinforcing assistant) moves Qi downward, breaks through the distension, and dries Dampness. Qing Pi (reinforcing assistant) breaks through Qi stagnation, particularly in the Liver and middle burner, helping to relieve the epigastric and flank fullness. Bai Zhu and Fu Ling (reinforcing assistants) work as a pair to strengthen the Spleen and drain Dampness, addressing the root condition of Spleen weakness that allows Dampness to accumulate.

Envoy herbs

Gan Cao harmonizes all the herbs, buffers the drying and Qi-breaking properties of the formula, and lends gentle Spleen support. The addition of fresh ginger (Sheng Jiang) in the decoction method further warms the middle and helps resolve Phlegm.

Notable synergies

Chai Hu paired with Huang Qin is the classical Shaoyang-resolving pair. Ban Xia paired with Hou Po powerfully dries Dampness and descends rebellious Qi. Bai Zhu paired with Fu Ling forms the fundamental Spleen-strengthening and Dampness-draining duo. Cao Guo combined with Qing Pi creates a strong aromatic penetration through turbid Dampness obstruction.

How to Prepare

Traditional preparation instructions for Qing Pi Tang

Grind the herbs coarsely. Use approximately 400 ml of water per dose. Add 5 slices of fresh ginger (Sheng Jiang). Bring to a boil, then simmer over low heat until reduced to about 200 ml. Strain and take warm on an empty stomach. The classical instruction is to take the decoction before the expected onset of the malarial episode. Typically taken once or twice daily.

Common Modifications

How practitioners adapt Qing Pi Tang for specific situations

Added
Qing Hao

9-15g, clears residual malarial Heat and vents it outward

Zhi Mu

6-9g, clears Heat and nourishes Yin to protect fluids

When Heat predominates over Dampness, adding Qing Hao specifically targets malarial Heat while Zhi Mu clears Heat without drying fluids, balancing the warming and drying herbs in the base formula.

Educational content — always consult a qualified healthcare provider or TCM practitioner before using any herbal formula.

Contraindications

Situations where Qing Pi Tang should not be used or requires extra caution

Avoid

Malarial disorders or intermittent fevers without underlying Dampness or Phlegm. This formula is specifically designed for cases where Dampness and Phlegm complicate the Shaoyang pattern. If the condition is purely Heat-based without turbid Dampness, different treatment strategies are needed.

Avoid

Yin deficiency with significant fluid depletion. The drying and aromatic herbs in this formula (Hou Po, Cao Guo, Ban Xia, Qing Pi) can further injure Yin and fluids. If the patient shows signs of dry mouth, red tongue with little coating, and a thin rapid pulse, this formula should be avoided or substantially modified.

Caution

Spleen and Stomach Qi deficiency without Dampness or Phlegm. The Qi-moving and Dampness-drying herbs can weaken an already deficient digestive system if Dampness is not present as the core pathology.

Caution

Use with caution in patients with a tendency toward loose stools from pure Spleen Yang deficiency (without Dampness), as the bitter and cold qualities of Huang Qin and the strong Qi-moving action of Qing Pi may further weaken digestion.

Special Populations

Important considerations for pregnancy, breastfeeding, and pediatric use

Pregnancy

Use with caution during pregnancy. Qing Pi (green tangerine peel) has a strong Qi-breaking action that could theoretically affect the uterus by forcefully moving Qi downward. Ban Xia (Pinellia) is traditionally listed among herbs that require caution in pregnancy due to its potent downward-directing and phlegm-resolving properties. While the formula overall is not classified as a strong abortifacient, the combination of Qi-moving and Dampness-drying herbs means pregnant patients should only use it under close practitioner supervision and only when the clinical need clearly outweighs potential risks.

Breastfeeding

No specific classical prohibitions exist for this formula during breastfeeding, but caution is warranted. Ban Xia (Pinellia) and Qing Pi (green tangerine peel) are potent herbs whose constituents could potentially transfer through breast milk. The formula's strongly drying nature may also reduce the production of breast milk by consuming body fluids. Breastfeeding mothers should consult a qualified TCM practitioner before use, and the formula should only be taken for the shortest effective duration.

Children

This formula may be used in children with appropriate dosage reduction, but only under professional supervision. General guidelines suggest reducing the adult dose to approximately one-third for children aged 6-12, and one-quarter or less for children under 6. The strong Qi-moving action of Qing Pi and the drying nature of Ban Xia, Hou Po, and Cao Guo require careful monitoring in children, whose Yin and fluids are more easily damaged. Prolonged use should be avoided. Not suitable for very young infants. A practitioner should closely monitor the child's appetite, energy, and stool quality during treatment.

Drug Interactions

If you are taking pharmaceutical medications, be aware of these potential interactions with Qing Pi Tang

Gan Cao (Licorice root) in this formula may interact with several classes of pharmaceuticals. Glycyrrhizin can cause pseudoaldosteronism (potassium loss and fluid retention), which may interfere with antihypertensive medications, diuretics (particularly potassium-depleting types like furosemide or thiazides), cardiac glycosides (such as digoxin, where hypokalemia increases toxicity risk), and corticosteroids (potentiating their mineralocorticoid effects).

Huang Qin (Scutellaria baicalensis) contains baicalin, which has been shown in pharmacological studies to affect cytochrome P450 enzymes. This could theoretically alter the metabolism of drugs processed through the CYP3A4 and CYP1A2 pathways. Patients taking immunosuppressants (e.g. cyclosporine), statins, or benzodiazepines should exercise caution.

Ban Xia (Pinellia) may interact with sedatives or CNS depressants by potentially enhancing their effects. Patients on antimalarial pharmaceuticals (e.g. chloroquine, artemisinin-based combinations) should inform their prescribing physician, as concurrent use of herbal and pharmaceutical antimalarials has not been well studied for interactions.

Usage Guidance

Practical advice for getting the most out of Qing Pi Tang

Best time to take

Traditionally taken warm, 30 minutes before meals, twice daily. For malarial conditions, ideally taken 1-2 hours before the expected onset of fever.

Typical duration

Acute use: typically 3-10 days, or until the cyclic fever pattern resolves. Reassess after each malarial cycle.

Dietary advice

While taking this formula, avoid greasy, oily, and fried foods that generate further Dampness and Phlegm. Cold and raw foods (such as salads, ice cream, and chilled drinks) should be minimized, as they can impair the Spleen's already weakened digestive function. Dairy products and excessively sweet foods tend to promote Phlegm production and should be reduced. Favor warm, lightly cooked, easily digestible meals such as rice porridge (congee), steamed vegetables, and mild soups. Small, frequent meals are preferred over large heavy meals to support the Spleen's recovery.

Qing Pi Tang originates from Jì Shēng Fāng (济生方, Formulas to Aid the Living) by Yán Yònghé (严用和) Sòng dynasty, 1253 CE

Classical Texts

Key passages from the classical Chinese medical texts that first described Qing Pi Tang and its clinical use

Source text (《济生方》 Jì Shēng Fāng):

Qing Pi Tang originates from Yan Yonghe's Ji Sheng Fang (Formulas to Aid the Living), published in 1253 during the Southern Song Dynasty. The formula was recorded in the chapter on malarial disorders (疟疾门), addressing intermittent fevers complicated by Dampness and Phlegm obstructing the Spleen. Specific original quotations from this text are difficult to verify with certainty beyond the formula composition and its indication for malarial conditions with Damp-Phlegm.

Related classical teaching on malaria and Shaoyang:

The Su Wen (Malaria Discussion chapter) states: 「疟气者,必更盛更虚,当气之所在也,病在阳,则热而脉躁;在阴,则寒而脉静」 — "The Qi of malaria necessarily alternates between excess and deficiency according to where it resides; when the illness is in the Yang, there is Heat with an agitated pulse; when in the Yin, there is Cold with a calm pulse." This classical understanding of malaria's alternating nature provides the theoretical foundation for Qing Pi Tang's Shaoyang-harmonizing strategy.

Historical Context

How Qing Pi Tang evolved over the centuries — its origins, lineage, and place in the broader tradition of Chinese medicine

Qing Pi Tang was created by Yan Yonghe (严用和), a distinguished physician of the Southern Song Dynasty, and recorded in his influential work Ji Sheng Fang (济生方, Formulas to Aid the Living), published in 1253. Yan Yonghe was known for his practical, clinically-oriented approach to medicine, and the Ji Sheng Fang became an important reference for generations of physicians treating common and complex conditions alike.

The formula represents an evolution of the Shaoyang-harmonizing tradition established by Zhang Zhongjing's Xiao Chai Hu Tang (Minor Bupleurum Decoction). Where Xiao Chai Hu Tang addresses a relatively straightforward Shaoyang pattern, Qing Pi Tang was designed for the more complicated clinical reality where malarial disorders were entangled with Damp-Phlegm accumulation due to Spleen weakness. By incorporating Dampness-transforming and Phlegm-resolving herbs alongside the classic Chai Hu and Huang Qin pair, Yan Yonghe created a formula specifically suited to the humid conditions of southern China, where malaria was endemic and patients often presented with concurrent Dampness. This reflects the Song Dynasty trend of refining classical formulas into more precisely targeted prescriptions for specific clinical subtypes.