Formula

Dan Shen Yin

Salvia Drink | 丹参饮

Also known as:

Dan Shen Yin Tang

Key Ingredients

Dan Shen

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Select Product Type

Select Supplier

Select Size

Quantity

$23.00 ($0.40/g)
Made to order · Non-cancellable once ordered · Policy
For shipments to: United States Change
Standard Shipping (3-5 business days): $4.99
Express Shipping (1-2 business days): $9.99
Free shipping on orders over $75

About This Formula

Traditional Chinese Medicine background and properties

Formula Description

A simple three-herb formula used to relieve chest and stomach pain caused by poor blood circulation and stagnant Qi. It works by promoting blood flow and easing Qi movement in the chest and abdomen. The source text notes it is especially effective for women.

Formula Category

Main Actions

  • Invigorates Blood and dispels stasis
  • Promotes the movement of Qi
  • Alleviates pain
  • Regulates Qi in the Middle Burner

TCM Patterns

In TCM, symptoms don't appear randomly — they cluster into recognizable patterns of disharmony that reveal what's out of balance in the body. Dan Shen Yin is traditionally associated with these specific patterns.

The following describes this formula's classification within Traditional Chinese Medicine theory and is provided for educational purposes only.

Why Dan Shen Yin addresses this pattern

Dan Shen Yin directly targets the combined pattern of Qi stagnation and Blood stasis in the Middle and Upper Burners. When Qi becomes stuck and Blood flow slows, this creates a self-reinforcing cycle: stagnant Qi fails to push Blood forward, and stagnant Blood physically blocks the channels, further impeding Qi flow. This produces fixed, stabbing, or boring pain in the chest and epigastrium that worsens under pressure. Dan Shen powerfully breaks through Blood stasis while Tan Xiang and Sha Ren restore the smooth movement of Qi, addressing both halves of the pathological cycle simultaneously.

A practitioner would look for one or more of these signs

Epigastric Pain Relieved With Pressure Or Eating

Stabbing or boring quality, fixed location, often worse after eating

Chest Pain

Oppressive pain with a sense of fullness or tightness

Abdominal Pain

Pain that resists pressure (refuses palpation)

Dark Complexion

Dull or purplish hue to lips or face

Amenorrhea

Menstrual pain with dark, clotted blood, especially in women

How It Addresses the Root Cause

Dan Shen Yin addresses a pattern of combined Qi stagnation and Blood stasis in the chest and upper abdomen, centered on the Heart and Stomach. In TCM theory, when emotional stress, dietary irregularity, or chronic illness causes Qi to stop flowing smoothly in the Middle Burner (the digestive center), Blood circulation also becomes obstructed — because Blood relies on Qi to propel it through the vessels. The classical teaching is: "where Qi goes, Blood follows; when Qi stagnates, Blood congeals."

In the early stages, Qi becomes knotted in the channels of the chest and epigastric region, producing a sensation of distension, fullness, and dull aching. Over time, as the renowned Qing-dynasty physician Ye Tianshi observed, "prolonged pain enters the collateral vessels" (久痛入络). The initially functional Qi stagnation gives rise to physical Blood stasis, with pain becoming more fixed, stabbing, and worsened by pressure. The Stomach, which normally descends Qi to digest food, loses its natural downward movement, leading to poor appetite and possible nausea. Because the Heart governs Blood circulation and shares the upper chest space, this stagnation can simultaneously manifest as chest tightness and cardiac-region pain. Women are said to be especially susceptible to this pattern because of the close relationship between Qi-Blood regulation and the menstrual cycle.

Dan Shen Yin works by directly invigorating Blood circulation to break up the stasis while simultaneously moving Qi to relieve the underlying stagnation that caused the Blood to congeal. By addressing both Qi and Blood simultaneously, it unblocks the channels so that "when flow is unimpeded, there is no pain" (通则不痛).

Formula Properties

Temperature

Slightly Warm

Taste Profile

Predominantly bitter and acrid (pungent) — bitter from Dan Shen to cool and move Blood, acrid from Tan Xiang and Sha Ren to warm, disperse, and move Qi.

Target Organs
Heart Stomach
Channels Entered
Heart Stomach Liver Spleen

Formula Origin

Shí Fāng Gē Kuò (时方歌括, Collected Songs on Modern Formulas) by Chén Niàn-Zǔ (Chen Xiu-Yuan)

This is just partial information on the formula's TCM properties. More detailed information is available on the formula's dedicated page

Ingredients in Dan Shen Yin

Detailed information about each herb in Dan Shen Yin and their roles

Kings
Assistants
Dan Shen
Dan Shen

Red sage roots

Dosage: 15 - 30g

Temperature Cool
Taste Bitter
Organ Affinity Heart, Liver
Parts Used Dried root and rhizome
Role in Dan Shen Yin

The principal herb, used in a dose five to ten times that of the other two ingredients. Dan Shen enters the Heart and Liver channels, powerfully invigorates Blood, dispels Blood stasis, and alleviates pain. It directly addresses the core pathomechanism of Blood stagnation in the Heart and Stomach.

Tan Xiang
Tan Xiang

Sandalwood

Dosage: 3 - 5g

Temperature Warm
Taste Pungent
Organ Affinity Spleen, Stomach, Heart, Lungs
Parts Used The wood
Role in Dan Shen Yin

Warms the Middle Burner, promotes Qi movement, and relieves pain in the chest and epigastrium. Since Blood circulation depends on the smooth flow of Qi, Tan Xiang supports Dan Shen by ensuring Qi moves freely so Blood can follow.

Sha Ren
Sha Ren

Amomum fruits

Dosage: 3 - 5g

Temperature Warm
Taste Pungent
Organ Affinity Kidneys, Spleen, Stomach
Parts Used Dried ripe fruit
Role in Dan Shen Yin

Moves Qi, warms the Middle Burner, loosens the chest, and harmonizes the Stomach. Works alongside Tan Xiang to address the Qi stagnation component, and also helps the Stomach receive and transform food, addressing the symptom of poor appetite or pain aggravated by eating.

Modern Research (3 studies)

  • Dan-Shen-Yin protects the heart against inflammation and oxidative stress induced by acute ischemic myocardial injury in rats (Preclinical study, 2012)
  • Network pharmacology and experimental analysis to reveal the mechanism of Dan-Shen-Yin against endothelial to mesenchymal transition in atherosclerosis (Preclinical/computational study, 2022)
See all research on the formula page

Usage & Safety

How to use this formula and important safety information

Important Medical Disclaimer

The information provided here is for educational purposes only and is not intended as medical advice or to replace consultation with a qualified healthcare professional. This formula is a dietary supplement and has not been evaluated by the FDA. It is not intended to diagnose, treat, cure, or prevent any disease.

Always consult with a qualified healthcare provider, particularly if you are pregnant, nursing, have a medical condition, or are taking other medications. Discontinue use and consult your healthcare provider if you experience any adverse reactions.

Recommended Dosage

Instructions for safe storage and consumption

Loading storage and consumption information...

Best Time to Take

30 minutes before meals, twice daily (morning and evening), to optimize absorption and direct the formula's action to the Stomach and Middle Burner.

Typical Duration

Acute pain episodes: 3–7 days. Chronic Qi stagnation and Blood stasis patterns (e.g. recurring epigastric pain, angina): 2–4 weeks, then reassessed by a practitioner.

Dietary Advice

While taking this formula, avoid cold and raw foods, icy drinks, and excessive greasy or heavy foods that may impair Qi circulation and worsen epigastric stagnation. Favor lightly cooked, warm meals that are easy to digest. Avoid alcohol in excess, as it generates Heat and can interact with the Blood-moving properties of the formula. Foods that gently support circulation, such as small amounts of hawthorn fruit, turmeric in cooking, or black vinegar, may complement the formula's action. If being used for Stomach pain, eat at regular times and in moderate portions — irregular eating habits contribute to Qi stagnation in the Middle Burner.

Special Populations

Pregnancy

Contraindicated during pregnancy. Dan Shen (Salvia miltiorrhiza), the chief ingredient making up the majority of this formula, is a potent Blood-invigorating herb that can stimulate uterine contractions and promote bleeding. Classical sources note it can "落死胎" (expel a dead fetus), indicating recognized abortifacient potential. Both Sha Ren and Tan Xiang are Qi-moving herbs that further increase the formula's dispersing nature. Pregnant women should avoid this formula entirely.

Breastfeeding

No specific classical prohibitions exist for use during breastfeeding, and the formula contains no known toxic substances. However, Dan Shen's active compounds (tanshinones and salvianolic acids) are pharmacologically potent and could theoretically pass into breast milk. Given the Blood-moving nature of the formula, it should be used with caution during the postpartum period and only under professional guidance. If there is no active Blood stasis condition requiring treatment, it is best avoided while nursing.

Pediatric Use

Dan Shen Yin is not a standard pediatric formula. The pattern it treats — Qi stagnation with Blood stasis causing epigastric or chest pain — is relatively uncommon in young children. If used in adolescents for appropriate indications (such as menstrual pain with Blood stasis), doses should be reduced to approximately one-third to one-half of the adult dose, adjusted by the child's age and body weight. A qualified practitioner should always supervise use in minors. This formula should generally not be used in children under 6 years of age.

Drug Interactions

Warfarin and other anticoagulants: This is the most important and well-documented interaction. Dan Shen (Salvia miltiorrhiza), the chief herb in this formula, significantly potentiates warfarin's anticoagulant effect through both pharmacokinetic mechanisms (increasing warfarin absorption, AUC, and half-life while decreasing clearance) and pharmacodynamic mechanisms (inherent antiplatelet and fibrinolytic activity). Multiple published case reports describe life-threatening bleeding complications including hemothorax when danshen was taken with warfarin. This combination should be strictly avoided.

Antiplatelet agents (aspirin, clopidogrel): Dan Shen inhibits platelet aggregation independently and may increase bleeding risk when combined with antiplatelet drugs. Research has also shown that Danshen preparations can alter clopidogrel's pharmacokinetics by inducing CYP enzymes. Use with caution and under medical supervision only.

Digoxin: Dan Shen may interfere with serum digoxin measurement assays, potentially leading to inaccurate monitoring results. This analytical interference could lead to inappropriate dose adjustments.

Drugs metabolized by CYP3A4: Tanshinones from Dan Shen have been shown to modulate cytochrome P450 enzymes, particularly CYP3A4. This could theoretically affect the metabolism of a wide range of pharmaceutical drugs processed by this pathway.

Contraindications

Avoid

Pregnancy. Dan Shen (Salvia miltiorrhiza) is a Blood-invigorating herb that can stimulate uterine activity and carries risk of promoting bleeding.

Avoid

Active hemorrhagic disorders or bleeding diathesis. The formula's Blood-moving action may worsen any active bleeding condition.

Avoid

Concurrent anticoagulant therapy (especially warfarin). Dan Shen has well-documented pharmacokinetic and pharmacodynamic interactions with warfarin that can cause dangerous over-anticoagulation.

Caution

Patients without Blood Stasis. This formula is designed for pain caused by Qi stagnation and Blood stasis. It should not be used for pain due to deficiency patterns, as its moving and dispersing nature could deplete a patient who is already weak.

Caution

Yin-deficiency or Blood-deficiency Heat patterns with no Stasis. Although Dan Shen has some mild cooling and Blood-nourishing properties, the formula as a whole is focused on moving, not supplementing.

Cautions & Warnings

Although this formula is typically safe for most individuals, it may cause side effects in some people. Pregnant women, nursing mothers, postpartum women, and those with liver disease should use the formula with caution.

As with any Chinese herbal remedy, it is advisable to seek guidance from a qualified TCM practitioner before beginning treatment.

Product Details

Manufacturing, supplier, and product specifications

Product Type

Granules

Quantity Description

Loading quantity information...

Concentration Ratio

Loading concentration information...

Fabrication Method

Loading fabrication information...

Supplier Certifications

Loading certifications information...

Supplier Information

Treasure of the East

Loading supplier information...

Loading supplier attributes...

Miscellaneous Info

No additional information available