Xing Su San

Apricot Kernel and Perilla Leaf Powder · 杏蘇散

Also known as: Apricot and Perilla Formula, Xing Su San

A classical formula used to treat autumn coughs with chills, thin phlegm, nasal congestion, and dry throat caused by cool, dry weather. It gently disperses the cold-dry pathogen from the body's exterior while restoring the Lung's ability to manage fluids and resolve phlegm.

Origin Wen Bing Tiao Bian (温病条辨, Systematic Differentiation of Warm Diseases) by Wu Jutong (吴鞠通) — Qīng dynasty, 1798 CE
Composition 11 herbs
Zi Su Ye
King
Zi Su Ye
Xing Ren
King
Xing Ren
Qian Hu
Deputy
Qian Hu
Jie Geng
Deputy
Jie Geng
Zhi Ke
Deputy
Zhi Ke
Ban Xia
Assistant
Ban Xia
Chen Pi
Assistant
Chen Pi
Fu Ling
Assistant
Fu Ling
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Educational content Consult qualified TCM practitioners for diagnosis and treatment

Patterns Addressed

In TCM, symptoms don't appear randomly — they cluster into recognizable patterns of disharmony that reveal what's out of balance in the body. Xing Su San is designed to correct these specific patterns.

Why Xing Su San addresses this pattern

Cool-dryness (凉燥, liáng zào) is a seasonal pathogenic factor that occurs in late autumn or early winter, when cool and dry climatic conditions invade the body. The Lung, which controls the skin and body hair, is the first organ affected. The cool aspect of the pathogen constricts the body surface, causing chills and blocking sweating, while the dry aspect damages the Lung's ability to spread and descend Qi, disrupting normal fluid distribution. Fluids that cannot be properly circulated accumulate as thin, watery phlegm. This formula gently disperses the cool-dry pathogen from the exterior with Su Ye and Qian Hu, restores the Lung's descending function with Xing Ren, Jie Geng and Zhi Ke, and resolves the resulting phlegm with Ban Xia, Chen Pi and Fu Ling. The overall approach is mild and warm rather than strongly dispersing, matching the relatively superficial nature of this pathogen.

A practitioner would look for one or more of these signs

Chills

Mild chills without sweating

Headaches

Mild headache

Nasal Congestion

Nasal congestion and stuffiness

Dry Throat

Dry or blocked sensation in the throat

Thin White Tongue Coating

Thin white tongue coating with wiry (string-like) pulse

Commonly Prescribed For

These conditions can arise from the patterns above. A practitioner would consider Xing Su San when these conditions are specifically caused by those patterns — not for all cases of these conditions.

Arises from: Cool-Dryness attacking the Lung Exterior-Cold

TCM Interpretation

In TCM, the common cold is understood as an invasion of external pathogenic factors through the body's defensive layer. In autumn, the dominant climatic factor is dryness, which combines with cooling temperatures to produce "cool-dryness." This pathogen attacks the Lung through the skin and nose, blocking the Lung's ability to properly spread defensive Qi and distribute fluids. The result is chills, nasal stuffiness, a dry or scratchy throat, and a cough producing thin, watery phlegm. The thin phlegm indicates that fluids are pooling internally because the Lung cannot move them properly, rather than the thick, sticky phlegm seen in heat conditions.

Why Xing Su San Helps

Xing Su San addresses autumn colds on multiple levels. Su Ye gently opens the body surface to release the trapped pathogen through mild sweating, while Xing Ren restores the Lung's descending function to stop the cough. The Deputy herbs Qian Hu, Jie Geng, and Zhi Ke ensure that Qi flows smoothly in both directions through the airway, relieving nasal and throat stuffiness. Ban Xia, Chen Pi, and Fu Ling resolve the accumulated thin phlegm and support the Spleen to prevent more from forming. This multi-layered approach makes it particularly effective for the type of cough and congestion typical of cool, dry weather.

Also commonly used for

Influenza

Mild influenza with chills, cough and nasal congestion

Acute Bronchitis

Early-stage bronchitis with watery sputum and chills

Emphysema

Cough and shortness of breath in emphysema aggravated by cold-dry conditions

Upper Respiratory Tract Infections

With predominant cough, nasal stuffiness and thin phlegm

What This Formula Does

Every TCM formula has a specific set of actions — here's what Xing Su San does in the body, explained in both everyday and TCM terms

Therapeutic focus

In practical terms, Xing Su San is primarily used to support these areas of health:

TCM Actions

In TCM terminology, these are the specific therapeutic actions that Xing Su San performs to restore balance in the body:

How It Addresses the Root Cause

TCM doesn't just suppress symptoms — it aims to resolve the underlying imbalance. Here's how Xing Su San works at the root level.

Xing Su San addresses a specific seasonal pattern called Cool Dryness (凉燥), which typically occurs in late autumn when the air becomes both cold and dry. During this season, the cool, arid climate creates a pathogenic factor that combines aspects of Cold and Dryness. This is distinct from the scorching dry-heat of early autumn (Warm Dryness), and also milder than a full-blown Wind-Cold invasion.

The Lungs govern the skin surface and connect directly to the nose and throat. When Cool Dryness attacks from outside, it first tightens the skin and blocks the pores, producing mild chills without sweating and a slight headache — symptoms that resemble a mild common cold. Because the pathogen is weaker than true Cold, the headache is only mild (not the splitting headache of severe Cold Damage). The cold, dry air then enters the Lungs and disrupts their core function of distributing fluids and directing Qi downward. Instead of being spread evenly throughout the body, fluids pool and congeal into thin, watery phlegm, producing cough with clear or thin sputum. The nose becomes blocked because the Lungs can no longer ventilate their opening (the nostrils), and the throat feels dry because fluids are not being properly distributed — a hallmark of the dryness component.

The wiry pulse and white tongue coating confirm two things: Cool Dryness is present at the surface, and thin phlegm-fluid (痰饮) has formed internally. The wiry quality also reflects the constraining nature of autumn's Metal Qi upon the Liver (Wood), adding a tension to the pulse. The overall picture is one of a mild exterior blockage combined with internal Lung Qi dysfunction and fluid maldistribution — not yet deep or severe, but requiring gentle release of the exterior alongside restoration of the Lung's dispersing and descending functions and transformation of accumulated phlegm.

Formula Properties

Every formula has an inherent temperature, taste, and affinity for specific organs — these properties determine how it interacts with the body

Overall Temperature

Slightly Warm

Taste Profile

Predominantly pungent and bitter with a mild sweet note — pungent to disperse the exterior and move Qi, bitter to direct Lung Qi downward and dry Dampness, sweet to harmonize and support the middle.

Channels Entered

Ingredients

11 herbs

The herbs that make up Xing Su San, organized by their role in the prescription

King — Main ingredient driving the formula
Deputy — Assists and enhances the King
Assistant — Supports or moderates other herbs
Envoy — Directs the formula to its target
Kings — Main ingredient driving the formula
Zi Su Ye

Zi Su Ye

Perilla leaves

Dosage 6 - 9g
Temperature Warm
Taste Pungent
Organ Affinity Lungs, Spleen

Role in Xing Su San

Warm and acrid but not overly drying, Su Ye releases the exterior and disperses cool-dryness from the skin and muscles, while also promoting the smooth flow of Lung Qi. It allows the pathogen to exit through the body surface via gentle sweating.
Xing Ren

Xing Ren

Apricot seeds

Dosage 6 - 9g
Temperature Warm
Taste Bitter, Sweet
Organ Affinity Large Intestine, Lungs

Role in Xing Su San

Bitter, slightly warm and moistening, Xing Ren descends Lung Qi to stop coughing, while also gently moistening dryness. Paired with Su Ye, it creates a complementary action of outward dispersal and downward direction, addressing both the exterior pathogen and the interior cough.
Deputies — Assists and enhances the King
Qian Hu

Qian Hu

Hogfennel roots

Dosage 6 - 9g
Temperature Cool
Taste Bitter, Pungent
Organ Affinity Spleen, Lungs

Role in Xing Su San

Assists Su Ye in dispersing the exterior pathogen by gently releasing Wind, while also helping Xing Ren direct Qi downward and transform phlegm. Bridges both the exterior-releasing and phlegm-resolving strategies of the formula.
Jie Geng

Jie Geng

Platycodon roots

Dosage 3 - 6g
Temperature Neutral
Taste Bitter, Pungent
Organ Affinity Lungs

Role in Xing Su San

Opens and lifts Lung Qi upward, working together with the downward-directing Zhi Ke to create balanced ascending and descending movement that unblocks the chest, clears the throat, and resolves phlegm.
Zhi Ke

Zhi Ke

Bitter oranges

Dosage 3 - 6g
Temperature Warm
Taste Bitter, Pungent, Sour
Organ Affinity Spleen, Stomach

Role in Xing Su San

Directs Qi downward and loosens the chest, complementing Jie Geng's lifting action. Together they restore normal ascending and descending of Lung Qi, alleviating cough, chest oppression, and phlegm stagnation.
Assistants — Supports or moderates other herbs
Ban Xia

Ban Xia

Crow-dipper rhizomes

Dosage 6 - 9g
Temperature Warm
Taste Pungent
Organ Affinity Lungs, Spleen, Stomach

Role in Xing Su San

Dries dampness and transforms phlegm, while also directing rebellious Qi downward to stop coughing and nausea. Addresses the internal accumulation of thin watery phlegm that results from impaired fluid distribution.
Chen Pi

Chen Pi

Tangerine peel

Dosage 3 - 6g
Temperature Warm
Taste Bitter, Pungent
Organ Affinity Lungs, Spleen

Role in Xing Su San

Regulates Qi in the Middle Burner and helps dry dampness to transform phlegm. Works alongside Ban Xia and Fu Ling to address the phlegm-dampness component from the digestive system.
Fu Ling

Fu Ling

Poria-cocos mushrooms

Dosage 6 - 9g
Temperature Neutral
Taste Sweet
Organ Affinity Heart, Kidneys, Lungs, Spleen

Role in Xing Su San

Strengthens the Spleen and promotes the healthy movement of fluids, cutting off phlegm production at its source. By supporting the Spleen's transforming and transporting function, it prevents further accumulation of dampness.
Sheng Jiang

Sheng Jiang

Fresh ginger

Dosage 3 slices
Temperature Warm
Taste Pungent
Organ Affinity Lungs, Spleen, Stomach

Role in Xing Su San

Warms the Middle Burner and assists Su Ye in releasing the exterior. Also harmonizes the protective (Wei) and nutritive (Ying) Qi layers, supporting recovery from external invasion.
Envoys — Directs the formula to its target
Da Zao

Da Zao

Jujube dates

Dosage 3 pieces
Temperature Warm
Taste Sweet
Organ Affinity Spleen, Stomach
Preparation Remove pit before use

Role in Xing Su San

Nourishes the Spleen and generates fluids, harmonizing the protective and nutritive Qi together with Sheng Jiang. Also moderates the drying tendency of the phlegm-resolving herbs.
Gan Cao

Gan Cao

Liquorice

Dosage 3g
Temperature Neutral
Taste Sweet
Organ Affinity Heart, Lungs, Spleen, Stomach

Role in Xing Su San

Harmonizes all the herbs in the formula and protects the Stomach. Combined with Jie Geng, it also benefits the throat. Its sweet flavor supplements the Middle Burner and moderates the acrid dispersing herbs.

Why This Combination Works

How the herbs in Xing Su San complement each other

Overall strategy

Cool-dryness has invaded from the outside and lodged in the Lung, blocking the Lung's ability to spread and descend Qi. At the same time, impaired fluid distribution has caused thin phlegm to accumulate internally. The formula therefore needs to gently disperse the exterior pathogen while simultaneously restoring the Lung's descending function and resolving phlegm. The approach follows the classical principle from the Su Wen: "When dryness dominates internally, treat with bitter and warm, assisted by sweet and acrid."

King herbs

Su Ye (Perilla Leaf) and Xing Ren (Apricot Kernel) form a complementary pair. Su Ye is acrid and warm but gentle, releasing the cool-dry pathogen from the body surface through mild sweating without being as forceful as herbs like Ma Huang. Xing Ren is bitter, slightly warm, and moistening, descending Lung Qi to stop coughing while adding a润 (moistening) quality appropriate for a dryness condition. Together, one pushes outward and upward, the other directs inward and downward, restoring the Lung's natural rhythm.

Deputy herbs

Qian Hu (Peucedanum) bridges both King herbs: it assists Su Ye in gently scattering exterior Wind while helping Xing Ren direct Qi downward and resolve phlegm. Jie Geng (Platycodon) and Zhi Ke (Bitter Orange) form a classic ascending-descending pair. Jie Geng lifts and opens the Lung Qi, while Zhi Ke directs it downward and widens the chest. Together they unblock stagnation in the airway and throat.

Assistant herbs

Ban Xia, Chen Pi, and Fu Ling form a reinforcing assistant group derived from the Er Chen Tang pattern. Ban Xia dries dampness and transforms the thin watery phlegm that accumulates when the Lung cannot properly distribute fluids. Chen Pi moves Qi and resolves phlegm in the Middle Burner. Fu Ling strengthens the Spleen to cut off phlegm production at its source. Sheng Jiang (Fresh Ginger) also serves as a restraining assistant, warming the Stomach to prevent the cold-natured phlegm from re-forming, while aiding Su Ye's exterior-releasing action.

Envoy herbs

Da Zao and Gan Cao anchor the formula. Da Zao nourishes Spleen Qi and generates fluids, paired with Sheng Jiang to harmonize the protective and nutritive layers. Gan Cao harmonizes all the ingredients and, in combination with Jie Geng, benefits the throat, directing therapeutic action to the upper airway.

Notable synergies

The Su Ye and Xing Ren pairing is the formula's signature: one opens the exterior (outward, upward) while the other descends the interior (inward, downward), together restoring the Lung's complete functional cycle. The Jie Geng and Zhi Ke pair creates a balanced "lifting and lowering" dynamic that loosens chest stagnation. The Ban Xia, Chen Pi, and Fu Ling trio mirrors Er Chen Tang's phlegm-resolving strategy, addressing the internal consequence of impaired Lung fluid distribution.

How to Prepare

Traditional preparation instructions for Xing Su San

Add all herbs to approximately 600 ml of water. Bring to a boil, then simmer on low heat for 20–25 minutes. Strain and serve warm. Take one dose per day, divided into two servings (morning and evening). The original text did not specify dosages, so modern standard dosages are used.

Common Modifications

How practitioners adapt Xing Su San for specific situations

Added
Qiang Huo

6–9g, to strengthen exterior dispersal and promote mild sweating

When the cool-dryness pathogen is strongly constricting the body surface, Su Ye alone may not be sufficient to open the pores. Qiang Huo's stronger dispersing action promotes mild sweating to release the exterior.

Educational content — always consult a qualified healthcare provider or TCM practitioner before using any herbal formula.

Contraindications

Situations where Xing Su San should not be used or requires extra caution

Avoid

Warm-Dryness (温燥) patterns: the formula contains predominantly warm, pungent herbs (Zi Su Ye, Ban Xia, Sheng Jiang, Chen Pi) that could worsen Heat or dry-Heat conditions. If the patient has dry cough with yellow sticky phlegm, fever, thirst, or a yellow tongue coating, this formula is inappropriate.

Avoid

Wind-Heat patterns: symptoms such as fever, sore throat, yellow nasal discharge, and a rapid floating pulse indicate Wind-Heat, which would be aggravated by the warming nature of this formula.

Caution

Severe external Cold with internal fluid retention (外寒内饮): though similar in presentation, conditions requiring the stronger diaphoretic and fluid-expelling power of Xiao Qing Long Tang (Minor Bluegreen Dragon Decoction) should not be treated with this milder formula, as its ability to expel Cold and drive out fluid accumulation is insufficient.

Avoid

Phlegm-Heat obstructing the Lungs: when cough features thick, yellow, difficult-to-expectorate phlegm with signs of Heat, the warming and drying herbs in this formula may worsen the condition.

Caution

Yin-deficient dry cough: patients with Lung Yin deficiency showing dry cough with scanty sputum, night sweats, and a red tongue with little coating should not take this formula, as Ban Xia and other drying herbs can further damage Yin fluids.

Special Populations

Important considerations for pregnancy, breastfeeding, and pediatric use

Pregnancy

Use with caution during pregnancy. Ban Xia (Pinellia rhizome) is traditionally classified as a pregnancy-caution herb (妊娠慎用). Research on Pinellia ternata has documented potential pregnancy toxicity and teratogenicity from its raw form, though the processed form (Fa Ban Xia or Zhi Ban Xia) used in clinical practice has significantly reduced toxicity. Xing Ren (apricot kernel) contains amygdalin, which can release small amounts of hydrogen cyanide upon metabolism, warranting caution in pregnancy. Gan Cao (licorice) in large doses has been associated with estrogenic activity and a possible risk of preterm delivery. While this formula uses mild doses of these herbs and is intended only for short-term acute use, pregnant women should consult a qualified practitioner before taking it. Some historical case reports describe the use of modified Xing Su San for pregnancy cough, but this should only be done under professional supervision.

Breastfeeding

No specific contraindication for breastfeeding has been established. The formula contains Ban Xia (Pinellia) and Gan Cao (licorice) in moderate doses. While there is no clinical evidence that licorice at these doses passes into breast milk in clinically significant amounts, its estrogenic activity at higher doses theoretically warrants awareness. Ban Xia in its processed form is considered generally safe at standard doses. As this is a short-course formula for acute respiratory symptoms, brief use under practitioner guidance is generally considered acceptable during breastfeeding. Nursing mothers should consult a qualified practitioner.

Children

Xing Su San has been used clinically in pediatric practice for children with acute bronchitis and upper respiratory infections presenting with a Cool Dryness or mild Wind-Cold pattern. Dosages should be reduced according to the child's age and weight — typically one-third to one-half of the adult dose for children aged 3 to 7, and two-thirds for children aged 7 to 14. For very young children (under 3), professional guidance is essential. Xing Ren (apricot kernel) contains amygdalin and should be used in appropriately small doses in children to avoid potential toxicity. Ban Xia should only be used in its processed form (Fa Ban Xia). The formula is generally well tolerated in short-term pediatric use and has been reported in Chinese clinical literature to effectively shorten the course of pediatric acute bronchitis with minimal adverse effects.

Drug Interactions

If you are taking pharmaceutical medications, be aware of these potential interactions with Xing Su San

Gan Cao (Licorice root, Glycyrrhiza): The glycyrrhizin in licorice can cause potassium loss and sodium retention. This may interact with diuretics (especially thiazides and loop diuretics), increasing the risk of hypokalemia. It may enhance the toxicity of cardiac glycosides (digoxin) through potassium depletion. Licorice may also reduce the effectiveness of antihypertensive medications by raising blood pressure, and may interact with corticosteroids by potentiating their effects through inhibition of cortisol metabolism. It may also interact with warfarin and other anticoagulants.

Xing Ren (Apricot kernel): Contains amygdalin, which releases trace hydrogen cyanide. No major drug interactions are well documented at standard decoction doses, but concurrent use with other cyanogenic substances should be avoided.

Ban Xia (Pinellia): In processed form, significant drug interactions are not well documented. However, its mucosal irritant potential in raw form warrants that only properly processed Ban Xia be used.

Overall, at the low doses and short duration typical of this formula, clinically significant drug interactions are uncommon. However, patients taking cardiac medications, antihypertensives, diuretics, or corticosteroids should inform their prescribing practitioner.

Usage Guidance

Practical advice for getting the most out of Xing Su San

Best time to take

Warm, after meals, twice daily (morning and evening). Taking after food helps protect the Stomach from the pungent and drying herbs.

Typical duration

Acute use: 3–7 days, reassessed if symptoms persist or change character.

Dietary advice

While taking this formula, avoid cold and raw foods (such as salads, iced drinks, raw fruit, and chilled dairy) as these can further constrict the Lung Qi and worsen phlegm accumulation. Greasy, fried, and heavily sweet foods should also be minimized, as they generate Dampness and Phlegm. Light, warm, easily digestible foods are best — warm congee (rice porridge), clear soups, lightly cooked vegetables, and ginger tea are all supportive. A small amount of pear cooked with ginger can gently moisten the throat while maintaining warmth. Avoid alcohol, as it generates Heat and Dampness that can complicate the pattern.

Xing Su San originates from Wen Bing Tiao Bian (温病条辨, Systematic Differentiation of Warm Diseases) by Wu Jutong (吴鞠通) Qīng dynasty, 1798 CE

Classical Texts

Key passages from the classical Chinese medical texts that first described Xing Su San and its clinical use

Wu Tang (吴瑭), Wen Bing Tiao Bian (《温病条辨》), Volume 1:

Original text: 「燥伤本脏,头微痛,恶寒,咳嗽稀痰,鼻塞,嗌塞,脉弦,无汗,杏苏散主之。」

Translation: "When Dryness injures its corresponding organ [the Lung], with slight headache, aversion to cold, cough with thin phlegm, nasal congestion, throat obstruction, a wiry pulse, and absence of sweating, Xing Su San governs it."


Wu Tang (吴瑭), Wen Bing Tiao Bian (《温病条辨》), Volume 1 — Formula Commentary:

Original text: 「燥伤皮毛,故头微痛恶寒也,微痛者,不似伤寒之痛甚也。……咳嗽稀痰者,肺恶寒,古人谓燥为小寒也;肺为燥气所搏,不能通调水道,故寒饮停而咳也。……按杏苏散,减小青龙汤一等。」

Translation: "Dryness injures the skin and body hair, hence the slight headache and aversion to cold. 'Slight' means it is not as severe as in Cold Damage disorders... Cough with thin phlegm occurs because the Lung detests cold — the ancients said dryness is akin to minor cold. The Lung, constrained by dry Qi, cannot regulate and circulate the waterways, so cold fluid retention accumulates and causes cough... Xing Su San is one grade milder than Xiao Qing Long Tang [Minor Bluegreen Dragon Decoction]."


Treatment Principle from the Su Wen, Zhi Zhen Yao Da Lun (《素问·至真要大论》), cited by Wu Tang:

Original text: 「燥淫于内,治以苦温,佐以甘辛。」

Translation: "When Dryness is excessive internally, treat with bitter and warm [herbs], assisted by sweet and pungent [herbs]." Wu Tang explicitly followed this principle in designing Xing Su San.

Historical Context

How Xing Su San evolved over the centuries — its origins, lineage, and place in the broader tradition of Chinese medicine

Xing Su San was created by Wu Tang (吴瑭, courtesy name Ju Tong 鞠通, 1758–1836), one of the most important physicians of the Warm Disease (温病) school, and published in his landmark work Wen Bing Tiao Bian (《温病条辨》, Systematic Differentiation of Warm Diseases). The book was initially drafted around 1798 and first printed in 1813. Wu Tang was from Huaiyin (present-day Jiangsu province) and was largely self-taught, having abandoned the civil service examination path after the deaths of his father and nephew from febrile diseases. He later studied at the Imperial Library while cataloguing medical texts within the Si Ku Quan Shu (Complete Library of the Four Treasuries) project.

The formula reflects a key theoretical debate in Chinese medicine history: the nature of autumn Dryness. While earlier physicians recognized Warm Dryness (温燥), the concept of Cool Dryness (凉燥) was articulated by Shen Mu'nan (沈目南, also known as Shen Mingzong 沈明宗) in his Zao Bing Lun (《燥病论》, Treatise on Dryness Diseases). Wu Tang explicitly drew on Shen's insight that autumn dryness could also manifest with cool, cold-like qualities. He designed Xing Su San as the representative formula for this pattern, positioning it as "one grade milder than Xiao Qing Long Tang" — powerful enough to release the exterior and transform phlegm, but gentle enough for a condition that is not a true severe Cold invasion. Interestingly, some modern scholars debate whether Xing Su San is truly a "Dryness-treating" formula at all, noting that its composition is overwhelmingly warm and pungent with little moistening action, and argue it functions more as a mild exterior-releasing formula for Wind-Cold with phlegm.

Wu Tang himself noted in his commentary that in his era, practitioners commonly used Xing Su San indiscriminately for all seasonal coughs. He cautioned against this, stressing it was specifically designed for Cool Dryness and should not replace formulas like Sang Ju Yin or Sang Xing Tang for Wind-Heat or Warm-Dryness patterns.