Wu Ji Bai Feng Wan

Black Chicken White Phoenix Pill · 乌鸡白凤丸

Also known as: Bai Feng Wan (白凤丸, White Phoenix Pill)

A famous women's health formula used to restore Qi and Blood when both are depleted, causing irregular periods, excessive vaginal discharge, physical weakness, lower back soreness, and fatigue. Built around whole black-boned chicken combined with nearly twenty herbs, it gently tonifies without being too heavy, making it one of the most widely used tonics in Chinese medicine.

Origin Shou Shi Bao Yuan (《寿世保元》) by Gong Tingxian (龚廷贤) — Ming dynasty, 1615 CE (refined by Qing dynasty imperial physicians)
Composition 20 herbs
Wu
King
Wu Ji
Shu Di Huang
Deputy
Shu Di Huang
Sh
Deputy
Sheng Di Huang (Raw Rehmannia Root)
Dang Gui
Deputy
Dang Gui
Bai Shao
Deputy
Bai Shao
Chuan Xiong
Deputy
Chuan Xiong
Lu
Assistant
Lu Jiao Jiao (Deer Antler Glue)
Ren Shen
Assistant
Ren Shen
+12
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Explore composition

Educational content Consult qualified TCM practitioners for diagnosis and treatment

Patterns Addressed

In TCM, symptoms don't appear randomly — they cluster into recognizable patterns of disharmony that reveal what's out of balance in the body. Wu Ji Bai Feng Wan is designed to correct these specific patterns.

Why Wu Ji Bai Feng Wan addresses this pattern

Qi and Blood deficiency is the core pattern this formula was designed to treat. When both Qi and Blood are insufficient, the body lacks the vital force to circulate nutrients and the material substance to nourish tissues. The formula addresses this with a comprehensive two-pronged approach: Wu Ji, Shu Di Huang, Dang Gui, Bai Shao, and Chuan Xiong powerfully nourish Blood, while Ren Shen, Huang Qi, Shan Yao, and Qian Shi replenish Qi and strengthen the Spleen (the source of Qi and Blood production). Lu Jiao Jiao supports the Kidney's role in generating Essence, the root material for both Qi and Blood. Dan Shen and Xiang Fu keep the newly tonified Qi and Blood circulating freely, while Gan Cao harmonises the entire composition.

A practitioner would look for one or more of these signs

Fatigue

Persistent tiredness and physical weakness

Irregular Menstruation

Scanty, pale, or delayed periods

Pale Complexion

Dull or sallow facial colour

Dizziness

Lightheadedness, especially on standing

Lower Back Pain

Soreness and weakness of the lower back and knees

Palpitations

Heart fluttering with exertion

Commonly Prescribed For

These conditions can arise from the patterns above. A practitioner would consider Wu Ji Bai Feng Wan when these conditions are specifically caused by those patterns — not for all cases of these conditions.

Arises from: Qi and Blood Deficiency Liver and Kidney Deficiency

TCM Interpretation

TCM understands menstruation as governed by the Chong and Ren extraordinary vessels, which depend on abundant Qi and Blood from the Spleen, Liver, and Kidney. When the Spleen fails to generate sufficient Qi, Blood production declines and the Spleen's holding function weakens, leading to erratic timing and pale, thin flow. When Liver Blood is deficient, it cannot fill the Chong vessel adequately, resulting in scanty periods. When Kidney Essence is insufficient, the Ren vessel loses its foundation, and cycles become irregular or stop altogether. This is a deficiency condition, distinct from menstrual irregularity caused by Qi stagnation, Blood stasis, or Heat in the Blood.

Why Wu Ji Bai Feng Wan Helps

Wu Ji Bai Feng Wan directly rebuilds the depleted substances. The black chicken (Wu Ji) broadly nourishes Blood and Essence. The Four Substances herbs (Shu Di Huang, Dang Gui, Bai Shao, Chuan Xiong) and Dan Shen replenish and circulate Blood. Ren Shen, Huang Qi, and Shan Yao strengthen Spleen Qi to restore Blood production at its source. Lu Jiao Jiao and Sang Piao Xiao fortify the Kidney and consolidate the Chong and Ren. Xiang Fu courses Liver Qi to regulate the menstrual cycle. Modern pharmacological research has shown the formula has sex hormone-like effects and can influence uterine smooth muscle activity, providing a possible mechanism for its menstrual-regulating action.

Also commonly used for

Dysmenorrhea

Menstrual pain with dull, dragging quality from deficiency

Vaginal Discharge

Chronic leukorrhea from Spleen and Kidney deficiency

Uterine Bleeding

Dysfunctional uterine bleeding (崩漏) from deficiency failing to hold Blood

Chronic Fatigue

Generalised weakness and tiredness from depleted Qi and Blood

Infertility

Female infertility associated with Qi and Blood or Kidney deficiency

Chronic Hepatitis

Chronic viral hepatitis with deficiency presentation

Thrombocytopenia

Primary immune thrombocytopenia with Qi and Blood deficiency

What This Formula Does

Every TCM formula has a specific set of actions — here's what Wu Ji Bai Feng Wan does in the body, explained in both everyday and TCM terms

Therapeutic focus

In practical terms, Wu Ji Bai Feng Wan is primarily used to support these areas of health:

TCM Actions

In TCM terminology, these are the specific therapeutic actions that Wu Ji Bai Feng Wan performs to restore balance in the body:

How It Addresses the Root Cause

TCM doesn't just suppress symptoms — it aims to resolve the underlying imbalance. Here's how Wu Ji Bai Feng Wan works at the root level.

This formula addresses a pattern of combined Qi and Blood deficiency, often accompanied by Liver and Kidney insufficiency and mild deficiency Heat. The underlying disease logic centres on the idea that Qi and Blood are mutually dependent: Qi drives the production and circulation of Blood, while Blood nourishes the organs that generate Qi. When both become depleted, a cascading cycle of decline sets in.

In the context of menstrual health, the Uterus (Bao Gong) depends on abundant Blood to produce a regular menstrual flow and on sufficient Qi to hold Blood within the vessels and discharge it in an orderly way. When Qi is weak, it cannot contain Blood properly, leading to irregular timing, prolonged spotting (崩漏, "flooding and leaking"), or excessive vaginal discharge. When Blood is deficient, periods become scanty, pale, and thin. The Liver stores Blood and the Kidneys store Essence, both of which nourish the Chong and Ren vessels that govern menstruation and reproduction. When these organs are depleted, the Chong and Ren lose their foundation, and menstrual disorders follow.

Chronic depletion of Yin and Blood also tends to generate mild internal Heat (deficiency Heat or "empty fire"), which can manifest as afternoon warmth, night sweats, irritability, and dry mouth. Additionally, when the Spleen and Kidney fail to consolidate fluids, vaginal discharge increases. The formula therefore needs to simultaneously tonify Qi, nourish Blood, supplement Liver and Kidney, clear deficiency Heat, and consolidate discharge, all without being so heavy or cloying that it stagnates the digestive system.

Formula Properties

Every formula has an inherent temperature, taste, and affinity for specific organs — these properties determine how it interacts with the body

Overall Temperature

Neutral

Taste Profile

Predominantly sweet with mild bitterness — sweet to tonify Qi, Blood, and Yin; slightly bitter to clear residual deficiency-heat; overall flavour is mild and harmonious.

Channels Entered

Liver Kidney Spleen Chong Mai (冲脉) Penetrating Vessel Ren Mai (任脉) Conception Vessel

Ingredients

20 herbs

The herbs that make up Wu Ji Bai Feng Wan, organized by their role in the prescription

King — Main ingredient driving the formula
Deputy — Assists and enhances the King
Assistant — Supports or moderates other herbs
Envoy — Directs the formula to its target
King — Main ingredient driving the formula
Wu

Wu Ji

Black-bone Chicken

Dosage 640g (per batch)
Temperature Neutral
Taste Sweet (甘 gān)
Organ Affinity Liver, Kidneys, Lungs
Preparation Eviscerated (intestines, feathers, and claws removed); stewed in rice wine with other herbs until wine is absorbed

Role in Wu Ji Bai Feng Wan

The principal substance of the formula. This whole-animal ingredient broadly tonifies Blood, nourishes Yin, supplements Liver and Kidney, and strengthens the Spleen. It provides the material foundation for restoring depleted Qi, Blood, and Essence.
Deputies — Assists and enhances the King
Shu Di Huang

Shu Di Huang

Prepared Rehmannia root

Dosage 256g (per batch)
Temperature Slightly Warm
Taste Sweet (甘 gān)
Organ Affinity Liver, Kidneys

Role in Wu Ji Bai Feng Wan

Nourishes Blood and supplements Yin, forming one part of the Four Substances combination. Its rich, nourishing quality fills depleted Blood and Essence.
Sh

Sheng Di Huang (Raw Rehmannia Root)

Dosage 256g (per batch)

Role in Wu Ji Bai Feng Wan

Clears Heat, cools Blood, and nourishes Yin. Balances the warming tonics in the formula and addresses deficiency Heat while supporting Blood production.
Dang Gui

Dang Gui

Chinese Angelica root

Dosage 144g (per batch)
Temperature Warm
Taste Sweet (甘 gān), Acrid / Pungent (辛 xīn)
Organ Affinity Liver, Heart, Spleen

Role in Wu Ji Bai Feng Wan

Tonifies and invigorates Blood, regulates menstruation. As a key member of the Four Substances group, it builds new Blood while gently moving it to prevent stasis.
Bai Shao

Bai Shao

White peony root

Dosage 128g (per batch)
Temperature Slightly Cool
Taste Bitter (苦 kǔ), Sour (酸 suān)
Organ Affinity Liver, Spleen

Role in Wu Ji Bai Feng Wan

Nourishes Blood, preserves Yin, softens the Liver, and alleviates pain. Completes the Four Substances combination and helps regulate menstruation.
Chuan Xiong

Chuan Xiong

Sichuan lovage rhizome

Dosage 64g (per batch)
Temperature Warm
Taste Acrid / Pungent (辛 xīn)
Organ Affinity Liver, Gallbladder, Pericardium

Role in Wu Ji Bai Feng Wan

Invigorates Blood and promotes Qi circulation, completing the Four Substances group. Its ascending and dispersing nature ensures Blood is not only built but moves freely.
Assistants — Supports or moderates other herbs
Lu

Lu Jiao Jiao (Deer Antler Glue)

Dosage 128g (per batch)

Role in Wu Ji Bai Feng Wan

Warms and supplements Kidney Yang, nourishes Essence and Blood, and strengthens the Chong and Ren vessels. Supports the Yang aspect of the Kidney to complement the Yin-nourishing herbs.
Ren Shen

Ren Shen

Ginseng root

Dosage 128g (per batch)
Temperature Slightly Warm
Taste Sweet (甘 gān), Bitter (苦 kǔ)
Organ Affinity Spleen, Lungs, Heart, Kidneys

Role in Wu Ji Bai Feng Wan

Powerfully tonifies original Qi, strengthens the Spleen, and supports the generation of Blood. Addresses the principle that Qi is needed to produce and govern Blood.
Xiang Fu

Xiang Fu

Nutgrass Galingale Rhizome

Dosage 128g (per batch)
Temperature Neutral
Taste Acrid / Pungent (辛 xīn), Bitter (苦 kǔ), Sweet (甘 gān)
Organ Affinity Liver, Spleen, San Jiao (Triple Burner)
Preparation Vinegar-prepared (醋制)

Role in Wu Ji Bai Feng Wan

Courses Liver Qi, regulates menstruation, and alleviates pain. Prevents the rich tonics from causing Qi stagnation and ensures smooth circulation.
Dan Shen

Dan Shen

Red sage root

Dosage 128g (per batch)
Temperature Slightly Cool
Taste Bitter (苦 kǔ)
Organ Affinity Heart, Liver, Pericardium

Role in Wu Ji Bai Feng Wan

Invigorates Blood and dispels stasis, cools Blood and calms the spirit. Prevents Blood stagnation from the heavy supplementing herbs and helps regulate menstruation.
Shan Yao

Shan Yao

Chinese yam

Dosage 128g (per batch)
Temperature Neutral
Taste Sweet (甘 gān)
Organ Affinity Spleen, Lungs, Kidneys

Role in Wu Ji Bai Feng Wan

Tonifies the Spleen and Kidney, consolidates Essence, and stops vaginal discharge. Supports digestion to help absorb the rich tonifying ingredients.
Bie Jia

Bie Jia

Turtle shell (Chinese soft-shell turtle carapace)

Dosage 64g (per batch)
Temperature Cool
Taste Salty (咸 xián)
Organ Affinity Liver, Kidneys
Preparation Vinegar-prepared (醋制)

Role in Wu Ji Bai Feng Wan

Nourishes Yin, subdues Yang, clears deficiency Heat, and softens hardness. Paired with the warming Lu Jiao Jiao to balance Yin and Yang supplementation.
Tian Men Dong

Tian Men Dong

Asparagus tuber

Dosage 64g (per batch)
Temperature Cold
Taste Sweet (甘 gān), Bitter (苦 kǔ)
Organ Affinity Lungs, Kidneys

Role in Wu Ji Bai Feng Wan

Nourishes Yin and moistens dryness, clears Lung and Kidney deficiency Heat. Supports the Yin-nourishing aspect of the formula.
Qian Shi

Qian Shi

Fox Nut

Dosage 64g (per batch)
Temperature Neutral
Taste Sweet (甘 gān), Astringent (涩 sè)
Organ Affinity Spleen, Kidneys
Preparation Stir-fried (炒)

Role in Wu Ji Bai Feng Wan

Strengthens the Spleen, consolidates the Kidney, stops vaginal discharge and diarrhoea. Its astringent quality helps contain leaking fluids.
Lu

Lu Jiao Shuang (Deer Antler Residue)

Dosage 48g (per batch)

Role in Wu Ji Bai Feng Wan

Mildly warms Kidney Yang, supplements Essence, and has an astringent quality that helps stop vaginal discharge and uterine bleeding. Less cloying than Lu Jiao Jiao, it lightens the formula.
Sang Piao Xiao

Sang Piao Xiao

Mantis egg-case

Dosage 48g (per batch)
Temperature Neutral
Taste Sweet (甘 gān), Salty (咸 xián)
Organ Affinity Liver, Kidneys

Role in Wu Ji Bai Feng Wan

Supplements the Kidney, consolidates Essence, and restrains urination and discharge. Supports the Kidney's function of holding and storing.
Mu

Mu Li (Oyster Shell)

Dosage 48g (per batch)
Preparation Calcined (煅)

Role in Wu Ji Bai Feng Wan

Calms the spirit, astringes fluids, and subdues floating Yang. Helps control sweating, discharge, and restlessness associated with deficiency.
Huang Qi

Huang Qi

Astragalus root

Dosage 32g (per batch)
Temperature Slightly Warm
Taste Sweet (甘 gān)
Organ Affinity Spleen, Lungs

Role in Wu Ji Bai Feng Wan

Tonifies Qi, raises Yang, consolidates the exterior, and supports the Spleen. Works with Ren Shen to strongly supplement Qi as the foundation for Blood production.
Yin Chai Hu

Yin Chai Hu

Stellaria root

Dosage 26g (per batch)
Temperature Slightly Cool
Taste Sweet (甘 gān)
Organ Affinity Liver, Stomach

Role in Wu Ji Bai Feng Wan

Clears deficiency Heat and cools the Blood without damaging Yin. Specifically targets the low-grade fever and night sweats of chronic depletion.
Envoy — Directs the formula to its target
Gan Cao

Gan Cao

Licorice root

Dosage 32g (per batch)
Temperature Neutral
Taste Sweet (甘 gān)
Organ Affinity Heart, Lungs, Spleen, Stomach

Role in Wu Ji Bai Feng Wan

Harmonises all the other herbs in the formula, moderates harshness, and gently tonifies Spleen Qi. Acts as a mediator among the diverse ingredients.

Why This Combination Works

How the herbs in Wu Ji Bai Feng Wan complement each other

Overall strategy

Because the patient presents with depletion across multiple dimensions (Qi, Blood, Yin, Yang, Liver, Kidney, Spleen), the formula adopts a broad-spectrum tonifying approach. It centres on a whole-animal substance to replenish Essence and Blood comprehensively, then layers in herbs that tonify Qi, nourish Blood, supplement Kidney, clear residual deficiency Heat, and astringe leaking fluids.

King herbs

Wu Ji (black-boned chicken, 640g) is the anchor of the formula, comprising roughly a quarter of the total weight. It is sweet and neutral, entering the Liver and Kidney channels, and has a uniquely broad tonic action: it supplements Blood and Yin, tonifies the Liver and Kidney, and strengthens the Spleen. As a whole-animal substance rich in protein and minerals, it provides the material foundation for rebuilding depleted Essence and Blood.

Deputy herbs

The "Four Substances" group (Shu Di Huang, Dang Gui, Bai Shao, Chuan Xiong) forms a classical Blood-nourishing and Blood-moving combination. Shu Di Huang and Sheng Di Huang (used together at high doses of 256g each) heavily nourish Blood and Yin. Dang Gui (144g) both supplements and moves Blood, preventing stasis while building new Blood. Dan Shen reinforces Blood invigoration, preventing the rich tonics from causing stagnation.

Assistant herbs

Reinforcing assistants: Ren Shen, Huang Qi, Shan Yao, and Qian Shi tonify Spleen Qi and strengthen the source of Blood production. Qi generation supports the principle that "Qi is the commander of Blood." Lu Jiao Jiao and Lu Jiao Shuang supplement Kidney Yang, nourish Essence, and strengthen the Chong and Ren vessels. Sang Piao Xiao further supports the Kidney's consolidation function.

Restraining assistants: Tian Men Dong, Yin Chai Hu, and Bie Jia (vinegar-prepared turtle shell) cool deficiency Heat and nourish Yin, preventing the warming and supplementing herbs from generating internal Heat. Xiang Fu (vinegar-prepared) courses Liver Qi and regulates menstruation, preventing the heavy tonics from creating Qi stagnation.

Astringent assistants: Mu Li (calcined oyster shell), Qian Shi, and Sang Piao Xiao consolidate the Kidney and astringe discharge, directly addressing leukorrhea and urinary issues.

Envoy herbs

Gan Cao harmonises all the other herbs in the formula and moderates any harshness, while also gently supporting Spleen Qi.

Notable synergies

The pairing of Lu Jiao Jiao (warming, Yang-supplementing) with Bie Jia (cooling, Yin-nourishing) achieves the classical principle of "seeking Yang within Yin and Yin within Yang," ensuring balanced restoration without tilting too warm or too cold. The simultaneous use of Sheng Di Huang (raw, cooling) and Shu Di Huang (prepared, warming and nourishing) covers both Blood nourishment and Yin cooling. Xiang Fu paired with Dan Shen ensures Qi and Blood move freely so the heavy tonics do not cause congestion.

How to Prepare

Traditional preparation instructions for Wu Ji Bai Feng Wan

Wu Ji Bai Feng Wan is a prepared patent medicine (中成药), not typically compounded as a raw-herb decoction in modern practice. It is commercially available as honey pills (大蜜丸, 9g per pill), small honey pills (小蜜丸), or water-honey pills (水蜜丸). The excipients used are honey (蜂蜜) and rice wine (黄酒).

Traditional preparation (historical): According to the Shou Shi Bao Yuan, the original method involved taking a whole white-feathered black-boned chicken (3 to 5 years old), removing the feathers and entrails. Powdered herbs were stuffed into the chicken's body cavity. The chicken was then placed in a copper pot and cooked with water and wine until dry. The cooked chicken meat and herbs were removed, deboned, dried, ground to powder, and formed into pills with glutinous rice paste.

Modern commercial preparation: Per the 2015 Chinese Pharmacopoeia, the 20 ingredients (totalling approximately 2554 grams) are processed, powdered, and combined with honey and rice wine to form pills. The standard large honey pill weighs 9 grams. Dosage is typically 1 pill (9g) taken orally, 1 to 2 times daily, or 6g of water-honey pills taken twice daily, swallowed with warm water.

Common Modifications

How practitioners adapt Wu Ji Bai Feng Wan for specific situations

Added
Dang Shen

15 - 30g, reinforces Spleen Qi

Bai Zhu

10 - 15g, strengthens Spleen and dries Dampness

When Qi deficiency is the dominant complaint with marked fatigue, poor appetite, and spontaneous daytime sweating, additional Qi tonics strengthen the Spleen's capacity to generate both Qi and Blood.

Educational content — always consult a qualified healthcare provider or TCM practitioner before using any herbal formula.

Contraindications

Situations where Wu Ji Bai Feng Wan should not be used or requires extra caution

Avoid

Pregnancy. The formula is officially listed as contraindicated during pregnancy (孕妇禁用). It contains Blood-moving herbs such as Dan Shen (Salvia), Chuan Xiong (Ligusticum), and Xiang Fu (Cyperus) that may stimulate uterine activity.

Avoid

Active external pathogen (common cold or flu). Taking tonifying herbs during an infection can trap the pathogen inside the body, a phenomenon called 'closing the door on the thief' (闭门留寇). Wait until the cold or fever has fully resolved before taking this formula.

Avoid

Excess-Heat or Damp-Heat patterns. This formula is designed for deficiency conditions. If menstrual irregularity, vaginal discharge, or pain is caused by Damp-Heat or Blood-Heat excess patterns (signs include thick yellow tongue coating, foul-smelling discharge, dark red tongue), the formula is inappropriate.

Caution

Blood stasis or Qi stagnation as the primary pattern. If menstrual pain or irregularity is mainly caused by Qi stagnation and Blood stasis rather than Qi and Blood deficiency, a different treatment strategy is needed.

Caution

Heavy menstrual bleeding (menorrhagia). The formula contains herbs that invigorate Blood (Dan Shen, Chuan Xiong, Xiang Fu), which may increase bleeding. It should not be taken during active heavy menstrual flow.

Caution

Diabetes patients should use under medical supervision, as the traditional pill form uses honey as a binder, which adds sugar content.

Caution

Patients with severe chronic conditions including hypertension, heart disease, liver disease, or kidney disease should only take this formula under the guidance of a qualified practitioner.

Caution

Known allergy to any ingredient in the formula. Those with an allergic constitution should use with caution.

Special Populations

Important considerations for pregnancy, breastfeeding, and pediatric use

Pregnancy

Contraindicated during pregnancy (孕妇禁用). The formula contains several herbs that invigorate Blood circulation, including Dan Shen (Salvia miltiorrhiza), Chuan Xiong (Ligusticum chuanxiong), and Xiang Fu (Cyperus rotundus). These have the potential to stimulate uterine contractions and increase blood flow to the uterus. Preclinical research has also shown the formula can influence uterine tone and hormonal levels (estrogen and progesterone), making it unsuitable during pregnancy. Women who are pregnant or suspect they may be pregnant should not take this formula.

Breastfeeding

No specific contraindication for breastfeeding has been established, and the formula has traditionally been used for postpartum recovery. However, because it is a complex 20-ingredient formula containing potent tonics (Ren Shen/Ginseng, Lu Jiao Jiao/Deer Antler Glue) and Blood-moving herbs (Dan Shen, Chuan Xiong), some active compounds could theoretically transfer into breast milk. Breastfeeding mothers should consult a qualified practitioner before use. The honey binder adds sugar, which is generally not a concern for lactation but should be noted for mothers monitoring caloric intake.

Children

Wu Ji Bai Feng Wan is not recommended for children. Pharmacological research indicates it has hormone-like effects, including the ability to promote reproductive system development in immature animals, raising concerns about potential premature sexual development in children. The formula is specifically designed for adult women (and sometimes men) with Qi and Blood deficiency patterns, which is not a typical pediatric presentation. Adolescent girls who have not yet established regular menstrual cycles should only take this formula under the direct guidance of a qualified practitioner.

Drug Interactions

If you are taking pharmaceutical medications, be aware of these potential interactions with Wu Ji Bai Feng Wan

Anticoagulant and antiplatelet drugs (e.g. warfarin, aspirin, clopidogrel): The formula contains Dan Shen (Salvia miltiorrhiza) and Chuan Xiong (Ligusticum chuanxiong), both of which have demonstrated anticoagulant and antiplatelet effects in laboratory studies. Concurrent use may increase the risk of bleeding, bruising, or prolonged clotting time.

Ren Shen (Ginseng) interactions: The formula contains Ren Shen (Panax ginseng), which may interact with several drug classes. It may reduce the effectiveness of warfarin. It can also interact with MAO inhibitors and may potentiate or interfere with hypoglycaemic medications (insulin and oral diabetic drugs), potentially causing unpredictable blood sugar levels.

Gan Cao (Licorice root) interactions: Gan Cao may cause sodium and water retention, potentially reducing the effectiveness of antihypertensive drugs. It may also increase the risk of hypokalaemia when used alongside diuretics (especially thiazides and loop diuretics), corticosteroids, or cardiac glycosides such as digoxin.

Classical incompatibilities (中药配伍禁忌): The formula contains Ren Shen, which according to classical "Eighteen Incompatibles" (十八反) theory, is antagonised by Li Lu (Veratrum). It should not be taken concurrently with preparations containing Li Lu, Wu Ling Zhi (Trogopterus dung), or Zao Jia (Gleditsia). Tea and radish (Lai Fu Zi) are traditionally advised against during use, as they may reduce the formula's tonifying effect.

Usage Guidance

Practical advice for getting the most out of Wu Ji Bai Feng Wan

Best time to take

Taken on an empty stomach or 30 minutes before meals, 1 to 2 times daily, swallowed with warm water.

Typical duration

Usually taken for 1 to 3 months (often starting on day 5 of the menstrual cycle for 20 days per cycle, repeated for 3 cycles), then reassessed by a practitioner.

Dietary advice

Avoid cold and raw foods (salads, iced drinks, chilled fruit) and excessively spicy, greasy, or deep-fried foods while taking this formula, as these can impair the Spleen's ability to absorb the tonic ingredients. Avoid strong tea, coffee, and turnip/radish during the treatment course, as these are traditionally considered to counteract the effects of tonifying herbs, particularly Ren Shen (Ginseng). Favour warm, easily digestible, nourishing foods such as congee, soups, steamed vegetables, and moderate amounts of red meat, dark leafy greens, and black sesame. Black-boned chicken soup is a traditionally recommended food that complements the formula's actions. Avoid alcohol in excess, though the formula itself traditionally incorporates rice wine as an excipient to help guide the herbs into the Blood level.

Wu Ji Bai Feng Wan originates from Shou Shi Bao Yuan (《寿世保元》) by Gong Tingxian (龚廷贤) Ming dynasty, 1615 CE (refined by Qing dynasty imperial physicians)

Classical Texts

Key passages from the classical Chinese medical texts that first described Wu Ji Bai Feng Wan and its clinical use

《寿世保元》(Shòu Shì Bǎo Yuán) — Gong Tingxian (龚廷贤), Ming dynasty:

The Shou Shi Bao Yuan records the original "Wu Ji Wan" (乌鸡丸) and "Bai Feng Dan" (白凤丹) separately. On the Wu Ji Wan, it describes the preparation method using a whole black-boned chicken stuffed with herbal medicines and cooked in wine, for the treatment of women with a weakened body, irregular menstruation, fatigue, and vaginal discharge.

On the indications, the text states: "论妇女五劳七伤,五心烦热,心虚惊怕;经水来时,或前或后,或淡白或紫色时常注带下……久服都有功效。" (Discussing women's exhaustion from overwork and emotional strain, heat in the palms, soles, and chest, palpitations from Heart deficiency; when menstruation comes early or late, is pale or purple in colour, with persistent vaginal discharge... prolonged use will yield good results.)

《本草纲目》(Běn Cǎo Gāng Mù) — Li Shizhen, Ming dynasty, on the chief ingredient Wu Ji (乌骨鸡):

"治女人崩中带下,一切虚损诸病" (Treats women's uterine bleeding and vaginal discharge, and all kinds of deficiency-related illness.)

《本草备要》(Běn Cǎo Bèi Yào) on Wu Ji:

"乌骨鸡甘平,鸡属木而骨黑者属水,得水木之精气,故能益肝肾,退热,补虚。" (Black-boned chicken is sweet and neutral. Chicken belongs to Wood, and the black-boned variety belongs to Water. It obtains the essential Qi of both Wood and Water, and therefore benefits the Liver and Kidneys, clears deficiency heat, and supplements deficiency.)

Historical Context

How Wu Ji Bai Feng Wan evolved over the centuries — its origins, lineage, and place in the broader tradition of Chinese medicine

Wu Ji Bai Feng Wan traces its origins to the Ming dynasty physician Gong Tingxian (龚廷贤, also known as Gong Yunlin 龚云林), who was celebrated as the "Champion of Medicine" (医林状元). In his work Shou Shi Bao Yuan (《寿世保元》, Precious Mirror for Preserving Life), published in 1615, he recorded two separate formulas: "Wu Ji Wan" (乌鸡丸, Black Chicken Pill) and "Bai Feng Dan" (白凤丹, White Phoenix Elixir). These were both designed for women suffering from Qi and Blood deficiency with menstrual disorders. Gong Tingxian was from Jiangxi province, the traditional homeland of the prized Taihe silkie chicken (泰和乌鸡), and his familiarity with this ingredient's medicinal value was likely influenced by his local heritage.

During the Qing dynasty, imperial physicians at the court (太医院) combined and refined these two formulas, adjusting the composition to create a single, more broadly applicable prescription. This refined version became the famous "Wu Ji Bai Feng Wan" used as a palace medicine. Empress Dowager Cixi (慈禧太后) was reportedly a notable user of the formula, seeking its rejuvenating and anti-aging benefits. The formula was manufactured by the renowned Tongrentang (同仁堂) pharmacy, founded in 1669, which supplied medicines to the imperial court. This association with royalty greatly boosted the formula's fame among common people. It is said that two original Wu Ji Bai Feng Wan pills are still on display at the Palace Museum (故宫博物院) in Beijing.

The modern standardised version, included in the Chinese Pharmacopoeia, uses 20 ingredients and differs from the original Ming dynasty recipe, which included herbs like Fang Feng, Qiang Huo, and Hai Jin Sha that are no longer part of the formula. Earlier related formulas also appear in the Pu Ji Fang (《普济方》) and the Ji Yin Gang Mu (《济阴纲目》) by Wu Zhiwang, which records both a "Da Wu Ji Wan" (大乌鸡丸) and "Xiao Wu Ji Wan" (小乌鸡丸) with distinct compositions and indications.

Modern Research

5 published studies investigating the pharmacological effects or clinical outcomes of Wu Ji Bai Feng Wan

1

Bak Foong Pills Alter Uterine Quiescence: Possible Role in Alleviation of Dysmenorrhoeal Symptoms (Preclinical, 2009)

Rowlands DK, Cui YG, Wong HY, Gou YL, Chan HC. Cell Biology International, 2009, 33(12): 1207-1211.

This laboratory study investigated whether Bak Foong Pills (a variant of Wu Ji Bai Feng Wan) could directly affect uterine muscle contractions. Using isolated uterine tissue preparations, the researchers found that an ethanol extract of the pills stimulated uterine relaxation after oxytocin-induced contractions. A key active compound, tetramethylpyrazine (from Chuan Xiong), was shown to modulate intracellular calcium levels in a way that favours muscle relaxation. The findings suggest the formula may relieve menstrual pain by directly reducing uterine muscle tone.

Link
2

Bak Foong Pills Induce an Analgesic Effect by Inhibiting Nociception via the Somatostatin Pathway in Mice (Preclinical, 2012)

Park JA, Bhimani RV, Engel T, Rowlands DK, Chan HC. Cell Biology International, 2012, 36(5): 441-446.

This animal study examined whether Bak Foong Pills possess pain-relieving (analgesic) properties. After 3 days of treatment, the pills significantly reduced pain responses in a mouse writhing test. The analgesic effect was not due to blocking prostaglandin production (the mechanism used by common painkillers like ibuprofen), but rather through activation of somatostatin receptors (sst2 and sst4) in the spinal cord, representing a distinct pain-relief pathway.

PubMed
3

UHPLC-ESI/QTOF-MS Rapid Analysis of Chemical Constituents in Wu Ji Bai Feng Pill (Analytical, 2017)

Zheng Y, Dong T, Xu X, Yuan X, Fan C, Gao S, Yuan D. Journal of Chromatographic Science, 2017.

This analytical chemistry study used advanced mass spectrometry to comprehensively profile the chemical components of Wu Ji Bai Feng Wan. A total of 173 distinct compounds were identified, including flavonoids, tanshinones, phenolic acids, phthalides, triterpene saponins, and cyclopeptides. The method provides a foundation for quality control standardisation and future pharmacological studies on the formula's active compounds.

PubMed
4

Screening Bioavailable Quality Markers of Wu Ji Bai Feng Pill by Integrating Intestinal Absorption and Network Pharmacology (Preclinical/Analytical, 2020)

Duan S, Niu L, Yin T, Li L, Gao S, Yuan D, et al. Phytomedicine, 2020, 76: 153226.

This study developed a novel approach to identify which chemical components in the formula are actually absorbed into the body and biologically active. Using a Caco-2 intestinal cell model and network pharmacology analysis, the researchers identified key bioavailable marker compounds for quality control. The approach helps bridge the gap between chemical composition and actual therapeutic activity, offering more meaningful quality standards for the formula.

PubMed
5

Effects of Bak Foong Pill on Blood Coagulation and Platelet Aggregation (Preclinical, 2003)

Gou YL, Ho AL, Rowlands DK, Chung YW, Chan HC. Biological and Pharmaceutical Bulletin, 2003, 26(2): 241-246.

This laboratory study examined how Bak Foong Pills affect blood clotting. The ethanol extract significantly prolonged thrombin time in a dose-dependent manner and inhibited platelet aggregation. These findings suggest the formula has mild anticoagulant and anti-platelet properties, which is consistent with its traditional indication of invigorating Blood and may also explain why it should be used cautiously alongside anticoagulant medications.

PubMed

Research on TCM formulas is growing but still limited by Western clinical trial standards. These studies provide emerging evidence and should be considered alongside practitioner expertise.