Formula

Shao Fu Zhu Yu Tang

Fennel Seed & Corydalis Combination | 少腹逐瘀汤

Also known as:

Fennel & Corydalis Combination , Drive Out Stasis from the Lower Abdomen Decoction , Fennel & Corydalis Formula

Key Ingredients

Dang Gui, Pu Huang

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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About This Formula

Traditional Chinese Medicine background and properties

Formula Description

A classical formula designed to warm the lower abdomen, improve Blood circulation, and relieve pain. It is particularly well suited for women experiencing menstrual cramps, irregular periods, or fertility difficulties linked to Cold and Blood stasis in the pelvic area. The formula combines warming herbs with Blood-moving herbs to address both the underlying Cold and the resulting stagnation.

Formula Category

Main Actions

  • Invigorates Blood and dispels stasis
  • Warms the channels and disperses Cold
  • Moves Qi and alleviates pain
  • Regulates menstruation

TCM Patterns

In TCM, symptoms don't appear randomly — they cluster into recognizable patterns of disharmony that reveal what's out of balance in the body. Shao Fu Zhu Yu Tang is traditionally associated with these specific patterns.

The following describes this formula's classification within Traditional Chinese Medicine theory and is provided for educational purposes only.

Why Shao Fu Zhu Yu Tang addresses this pattern

This is the primary pattern this formula was designed for. When Cold pathogen lodges in the lower abdomen (the domain of the Liver channel and the Uterus), it causes Blood to congeal and Qi to stagnate. The Cold slows Blood circulation, leading to clotting and accumulation. The formula's warming triad (Xiao Hui Xiang, Gan Jiang, Guan Gui) directly dispels the Cold, while the large contingent of Blood-moving herbs (Dang Gui, Pu Huang, Wu Ling Zhi, Chuan Xiong, Chi Shao) breaks up the resulting stasis. The Qi-moving pain relievers (Yan Hu Suo, Mo Yao) ensure that Qi flow is restored alongside Blood flow, following the principle that Blood and Qi are inseparable.

A practitioner would look for one or more of these signs

Amenorrhea

Menstrual pain that is relieved by warmth and worsened by cold

Lower Abdominal Pain

Fixed, cramping pain in the lower abdomen

Dark Menstrual Clots

Dark purple or black menstrual blood with clots

Irregular Menstruation

Irregular cycle with frequent spotting or prolonged bleeding

Infertility

Difficulty conceiving due to Cold in the uterus

Cold Sensation In Lower Limbs

Cold sensation in the lower abdomen and limbs

How It Addresses the Root Cause

This formula addresses a pattern where Cold has lodged in the lower abdomen (the "Shao Fu" region, which includes the uterus, ovaries, and surrounding pelvic structures) and caused Blood to congeal and stagnate there. In TCM theory, Blood must circulate freely to nourish the body and support reproductive function. When Cold invades the lower burner or when internal Yang is insufficient to keep the lower abdomen warm, Blood congeals just as water freezes in winter. This stagnant Blood then obstructs the channels and collaterals of the pelvic region.

Once Blood stasis forms, it creates a vicious cycle: stagnant Blood blocks Qi movement, and stagnant Qi further impedes Blood flow. The result is pain, because "where there is obstruction, there is pain" (不通则痛). The pain is typically fixed in location, often worse with cold exposure, and may be accompanied by palpable masses in the lower abdomen. In women, the Chong and Ren vessels, which govern menstruation and fertility, pass through this region. When Cold and stasis block these vessels, menstrual blood cannot flow and discharge properly, leading to irregular periods, dark or clotted menstrual blood, painful periods, or even the complete cessation of menstruation. The stasis may also prevent the uterus from receiving and nourishing a fertilized embryo, causing infertility.

The key diagnostic indicators are: lower abdominal pain (often cold-type, relieved by warmth), dark or purplish menstrual blood with clots, a dark or purplish tongue (especially on the sides or tip), and a deep, choppy, or tight pulse. The formula's strategy is to simultaneously warm the channels to disperse Cold and invigorate Blood to dissolve stasis, addressing both the cause (Cold) and the consequence (Blood stasis) at the same time.

Formula Properties

Temperature

Warm

Taste Profile

Predominantly pungent and bitter with a warm aromatic quality. The pungent flavor (from Rou Gui, Gan Jiang, Xiao Hui Xiang, Chuan Xiong) drives circulation and disperses Cold; the bitter flavor (from Mo Yao, Wu Ling Zhi, Yan Hu Suo) moves Blood stasis and alleviates pain.

Target Organs
Liver Uterus Kidneys Spleen
Channels Entered
Liver Spleen Kidney Chong Mai (冲脉) Penetrating Vessel Ren Mai (任脉) Conception Vessel

Formula Origin

Yi Lin Gai Cuo (医林改错, Correction of Errors in Medicine) by Wang Qing Ren

This is just partial information on the formula's TCM properties. More detailed information is available on the formula's dedicated page

Ingredients in Shao Fu Zhu Yu Tang

Detailed information about each herb in Shao Fu Zhu Yu Tang and their roles

Kings
Deputies
Assistants
Dang Gui
Dang Gui

Dong quai

Dosage: 9 - 15g

Temperature Warm
Taste Pungent, Sweet
Organ Affinity Heart, Liver, Spleen
Parts Used Dried root
Role in Shao Fu Zhu Yu Tang

Nourishes and invigorates the Blood, regulates menstruation, and generates new Blood while dispersing stasis. As the herb with the largest dosage, it anchors the formula's Blood-moving action while preventing excessive consumption of Blood from the other stasis-dispelling ingredients.

Pu Huang
Pu Huang

Cattail pollen

Dosage: 9 - 12g

Temperature Neutral
Taste Sweet
Organ Affinity Spleen, Heart, Liver, Pericardium
Parts Used Dried pollen
Role in Shao Fu Zhu Yu Tang

Used raw (生蒲黄) in this formula to emphasize its Blood-invigorating and stasis-dispersing action. Together with Wu Ling Zhi it forms Shi Xiao San (Sudden Smile Powder), a potent pairing for activating Blood and stopping pain in the lower abdomen.

Wu Ling Zhi
Wu Ling Zhi

Flying squirrel faeces

Dosage: 6 - 9g

Temperature Warm
Taste Bitter, Sweet
Organ Affinity Spleen, Liver
Parts Used Dried faeces
Role in Shao Fu Zhu Yu Tang

Paired with Pu Huang to form Shi Xiao San, it activates Blood circulation, disperses stasis, and stops pain. Used dry-fried (炒) to strengthen its pain-stopping effect and reduce its tendency to upset the stomach.

Chuan Xiong
Chuan Xiong

Szechuan lovage roots

Dosage: 3 - 6g

Temperature Warm
Taste Pungent
Organ Affinity Gallbladder, Liver, Pericardium
Parts Used Dried rhizome
Role in Shao Fu Zhu Yu Tang

Known as the 'Qi herb within the Blood,' it powerfully moves both Qi and Blood. It reinforces the Blood-invigorating action of the Kings while ensuring that Qi circulation supports Blood movement, following the principle that when Qi moves, Blood follows.

Chi Shao
Chi Shao

Red peony roots

Dosage: 6 - 9g

Temperature Cool
Taste Bitter
Organ Affinity Liver
Parts Used Dried root
Role in Shao Fu Zhu Yu Tang

Clears Heat from the Blood, invigorates Blood, and disperses stasis. It complements Dang Gui by adding a cooling, stasis-clearing dimension that helps balance the warming nature of the formula and prevents the warm herbs from generating excessive Heat.

Xiao Hui Xiang
Xiao Hui Xiang

Fennel seeds

Dosage: 1.5 - 6g

Temperature Warm
Taste Pungent
Organ Affinity Kidneys, Liver, Spleen, Stomach
Parts Used Dried ripe fruits
Role in Shao Fu Zhu Yu Tang

Warms the Liver channel and lower abdomen, disperses Cold, and regulates Qi. It directs the warming action specifically to the lower abdomen and Liver channel, addressing the Cold that causes Blood to congeal.

Gan Jiang
Gan Jiang

Dried ginger

Dosage: 3 - 6g

Temperature Hot
Taste Pungent
Organ Affinity Heart, Kidneys, Lungs, Stomach
Parts Used Dried rhizome
Role in Shao Fu Zhu Yu Tang

Warms the interior, disperses Cold from the channels, and supports Yang. Works with Xiao Hui Xiang and Guan Gui to form the warming triad that addresses the root cause of Cold congealing Blood in the lower abdomen.

Rou Gui
Rou Gui

Cinnamon bark

Dosage: 3 - 6g

Temperature Hot
Taste Pungent, Sweet
Organ Affinity Heart, Kidneys, Liver, Spleen
Parts Used Dried stem bark
Role in Shao Fu Zhu Yu Tang

Powerfully warms the Kidney Yang and the channels, promotes Blood circulation by warming, and helps guide the other herbs to the lower body. It strengthens the warming strategy and encourages Blood flow through the pelvic vessels.

Yan Hu Suo
Yan Hu Suo

Corydalis tubers

Dosage: 3 - 9g

Temperature Warm
Taste Bitter, Pungent
Organ Affinity Spleen, Heart, Liver, Lungs
Parts Used Dried tuber
Role in Shao Fu Zhu Yu Tang

One of the most effective Qi-and-Blood-moving pain relievers in Chinese medicine. It targets both Qi stagnation and Blood stasis pain, significantly strengthening the formula's analgesic action.

Mo Yao
Mo Yao

Myrrh

Dosage: 3 - 6g

Temperature Neutral
Taste Bitter
Organ Affinity Spleen, Heart, Liver
Parts Used Dried resin of the tree
Role in Shao Fu Zhu Yu Tang

Disperses Blood stasis, reduces swelling, and alleviates pain. It complements Yan Hu Suo in strengthening the formula's pain-relieving capacity, particularly for fixed, stabbing pain from Blood stasis.

Modern Research (4 studies)

  • Systematic Review of RCTs: Shaofu Zhuyu Decoction for Primary Dysmenorrhea (2016)
  • Preclinical Study: SZD Regresses Endometriotic Lesions in a Rat Model (2018)
See all research on the formula page

Usage & Safety

How to use this formula and important safety information

Important Medical Disclaimer

The information provided here is for educational purposes only and is not intended as medical advice or to replace consultation with a qualified healthcare professional. This formula is a dietary supplement and has not been evaluated by the FDA. It is not intended to diagnose, treat, cure, or prevent any disease.

Always consult with a qualified healthcare provider, particularly if you are pregnant, nursing, have a medical condition, or are taking other medications. Discontinue use and consult your healthcare provider if you experience any adverse reactions.

Recommended Dosage

Instructions for safe storage and consumption

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Best Time to Take

30 minutes after meals, twice daily (morning and evening). For menstrual pain, begin taking on the first day of menstruation or 2-3 days before expected onset.

Typical Duration

Typically prescribed for 2-4 weeks initially, then reassessed. For menstrual conditions, often taken cyclically: starting from the first day of menstruation for 5-7 days per cycle, continuing for 3-4 menstrual cycles.

Dietary Advice

While taking this formula, favor warm, cooked foods that support circulation and digestive warmth. Ginger tea, warming soups and stews, lamb, and moderate amounts of warming spices (cinnamon, black pepper, fennel) are beneficial. Avoid cold and raw foods including salads, raw fruits, iced drinks, ice cream, and cold dairy products, as these can aggravate Cold accumulation in the lower abdomen and counteract the formula's warming effects. Also avoid excessively greasy or rich foods that may impair digestion and generate Dampness. During menstruation, particularly avoid sour foods (vinegar, citrus) which have an astringent quality that may impede the smooth discharge of menstrual blood.

Modern Usage

Clinically, it is primarily for chronic pelvic inflammatory disease, primary dysmenorrhea, endometriosis, tubal obstructive infertility, uterine fibroids, and other related conditions.

Special Populations

Pregnancy

Contraindicated during pregnancy. This formula contains several strongly Blood-moving herbs that can stimulate uterine contractions and increase the risk of miscarriage. Specifically: - Pu Huang (Cattail Pollen) and Wu Ling Zhi (Trogopterus Dung) are potent Blood-movers that promote uterine contraction. - Mo Yao (Myrrh) is a known Blood-moving resin with uterine-stimulating properties. - Yan Hu Suo (Corydalis) has analgesic and Blood-moving effects that are inappropriate in pregnancy. - Rou Gui (Cinnamon Bark) and Gan Jiang (Dried Ginger) are strongly warming and can promote downward movement of Blood. Note: Although Wang Qingren himself mentioned this formula could 'secure the fetus' in specific cases of Blood stasis threatening miscarriage, this was a specialized clinical judgment by an experienced practitioner. In general use, this formula must be avoided during pregnancy. Any use during pregnancy would require expert supervision by a qualified practitioner who can carefully assess the individual case.

Breastfeeding

Use with caution during breastfeeding. While there is no specific traditional prohibition against this formula during lactation, several considerations apply: - Mo Yao (Myrrh) and Wu Ling Zhi (Trogopterus Dung) are pungent, Blood-moving substances whose bioactive compounds may transfer into breast milk. Their safety profile during breastfeeding has not been established. - Rou Gui (Cinnamon Bark) in moderate doses is generally regarded as safe, but in the therapeutic doses used in this formula, its warming nature could theoretically affect breast milk quality. - The formula's strong Blood-moving action is generally unnecessary during uncomplicated breastfeeding and could theoretically affect milk production in some individuals. If postpartum Blood stasis with lower abdominal pain requires treatment during breastfeeding, a qualified practitioner should supervise use and may consider dose reduction or substitution of specific herbs.

Pediatric Use

This formula is not commonly used in pediatric practice. Wang Qingren did mention the use of his Zhu Yu Tang series for children with abdominal masses (痞块, pi kuai), but Shao Fu Zhu Yu Tang specifically targets gynecological and lower abdominal Blood stasis patterns that are predominantly adult conditions. If indicated in adolescents (post-menarche) for severe dysmenorrhea with clear Cold-stasis signs, the dosage should be reduced to approximately 1/2 to 2/3 of the adult dose depending on body weight and constitution. It is not appropriate for pre-pubescent children. Any pediatric use requires supervision by a qualified practitioner experienced in treating children.

Drug Interactions

Anticoagulant and antiplatelet medications (e.g. warfarin, heparin, aspirin, clopidogrel): Multiple herbs in this formula have demonstrated Blood-moving and anticoagulant-like effects. Dang Gui (Angelica sinensis) and Chuan Xiong (Ligusticum) are known to inhibit platelet aggregation. Pu Huang (Cattail Pollen) has documented hemostatic and anticoagulant dual properties. Concurrent use may increase bleeding risk and requires close monitoring of clotting parameters (INR/PT).

Hormonal medications and oral contraceptives: Because this formula strongly affects pelvic circulation and menstrual regulation, it may theoretically interact with hormonal therapies including oral contraceptives, hormone replacement therapy, or fertility drugs. Concurrent use should be coordinated with both the prescribing physician and TCM practitioner.

NSAIDs (non-steroidal anti-inflammatory drugs): Yan Hu Suo (Corydalis) contains alkaloids (notably dehydrocorybulbine and tetrahydropalmatine) with analgesic and sedative properties. Combining with NSAIDs may have additive effects on pain relief but could also compound gastrointestinal side effects.

Sedatives and CNS depressants: Yan Hu Suo (Corydalis) has mild sedative and analgesic properties that could theoretically potentiate the effects of benzodiazepines or opioid medications.

Contraindications

Avoid

Pregnancy. This formula contains multiple potent Blood-moving herbs (Pu Huang, Wu Ling Zhi, Mo Yao, Chuan Xiong) and warming herbs (Rou Gui, Gan Jiang) that can stimulate uterine contractions and risk miscarriage.

Avoid

Heavy menstrual bleeding (menorrhagia) due to Blood-Heat or Yin deficiency. The warming and Blood-moving nature of this formula can worsen excessive bleeding that is not caused by Blood stasis.

Avoid

Heat in the Blood (Blood-Heat patterns). This is a warm formula designed for Cold-stagnation Blood stasis. Using it for Heat-type gynecological conditions can aggravate the condition.

Caution

Patients taking anticoagulant or antiplatelet medications. The strong Blood-moving properties may compound bleeding risk.

Caution

Significant Qi or Blood deficiency without concurrent stasis. If the patient is severely depleted, the formula's moving and dispersing actions may further drain the body's resources. Tonifying herbs should be added if stasis coexists with deficiency.

Caution

Perioperative period. Due to its Blood-invigorating effects, the formula should be discontinued at least 1-2 weeks before and after surgery to reduce bleeding risk.

Cautions & Warnings

This formula is generally safe for most people, but it may cause side effects in some instances. It is not recommended during pregnancy or for those with spotting due to Blood Deficiency.

As with any Chinese herbal remedy, it is advisable to seek guidance from a qualified Traditional Chinese Medicine (TCM) practitioner before beginning treatment.

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Manufacturing, supplier, and product specifications

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