Formula

Ren Shen Bai Du San

Ginseng & Mentha Formula | 人参败毒散

Also known as:

Ginseng Powder to Overcome Pathogenic Influences , Shi Wei Tang , Ten-Ingredient Decoction

Properties

Exterior-releasing formulas · Warm

Key Ingredients

Qiang Huo, Du Huo

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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About This Formula

Traditional Chinese Medicine background and properties

Formula Description

A classical formula designed for people whose bodies are already somewhat weakened when they catch a cold or flu with chills, body aches, and dampness. It combines herbs that expel wind, cold, and dampness from the body's surface with Ginseng, which strengthens the body's Qi so it has enough force to push the illness out. Historically famous as a treatment for epidemics and early-stage dysentery.

Formula Category

Main Actions

  • Disperses Wind-Cold
  • Expels Dampness
  • Tonifies Qi
  • Releases the Exterior
  • Alleviates pain
  • Resolves Phlegm

TCM Patterns

In TCM, symptoms don't appear randomly — they cluster into recognizable patterns of disharmony that reveal what's out of balance in the body. Ren Shen Bai Du San is traditionally associated with these specific patterns.

The following describes this formula's classification within Traditional Chinese Medicine theory and is provided for educational purposes only.

Why Ren Shen Bai Du San addresses this pattern

This is the primary pattern for which Ren Shen Bai Du San was designed. When a person's Qi is already insufficient (from constitutional weakness, old age, childhood, post-illness recovery, or postpartum), they are particularly vulnerable to invasion by Wind, Cold, and Dampness. The external pathogens block the body surface and obstruct the channels, causing chills, fever without sweating, and widespread body pain. Simultaneously, internal Qi deficiency means the body cannot muster enough force to push the pathogens out on its own. The formula addresses both sides: Qiang Huo and Du Huo powerfully expel Wind-Cold-Damp, Chai Hu and Chuan Xiong assist in releasing the exterior and moving stagnation, while Ren Shen and Fu Ling quietly support the Qi and resolve Dampness from within. The key clinical clue distinguishing this pattern from simple Wind-Cold is the pulse: it floats (indicating exterior involvement) but feels weak or forceless on deeper pressure (indicating underlying Qi deficiency).

A practitioner would look for one or more of these signs

Chills

Strong chills (憎寒壮热) with simultaneous fever

Headaches

Headache with stiff, painful neck

Body Pain

Generalized aching and heaviness of the limbs

Absence of Sweating

No sweating despite fever

Nasal Congestion

Nasal congestion with heavy voice

Hypochondrial Pain That Is Worse On Coughing And Breathing

Cough with white sputum

Chest Stiffness

Fullness and stuffiness in the chest and diaphragm

Eye Fatigue

Underlying fatigue and weakness

How It Addresses the Root Cause

This formula addresses a situation where a person with underlying Qi weakness catches an external illness caused by Wind, Cold, and Dampness. Because their Qi is already insufficient, their body's protective barrier (the Wei Qi, or defensive Qi) is unable to mount a strong response to push the invading pathogens out. The Cold and Dampness settle into the muscles, joints, and surface layers of the body, blocking the normal circulation of Qi and Blood. This produces symptoms like strong chills with fever, absence of sweating, stiff and painful neck and head, heavy aching limbs, nasal congestion, and coughing with phlegm. The tongue coating is typically white and greasy, and the pulse floats but feels weak when pressed firmly, reflecting both the surface invasion and the underlying deficiency.

The critical insight of this formula is that simply using strong dispersing herbs to push out the pathogen will not work well in a Qi-deficient person. As the physician Yu Chang explained, in someone whose Qi is weak, the medicine may push the pathogen partway out but lack the force to expel it completely, leaving the patient stuck in a lingering, half-resolved illness. Or worse, the pathogen may follow the weakened Qi back inward and sink deeper. By adding a small amount of Ginseng to support the Qi from within, the body gains just enough strength for the dispersing herbs to work effectively, allowing the pathogen to surge out all at once. This same logic applies to the formula's famous use in early-stage dysentery with exterior symptoms: when external pathogens that were not properly expelled from the surface have sunk inward and entered the intestines, this formula can "reverse the current and steer the boat upstream" (the celebrated "ni liu wan zhou" method), lifting the sunken pathogen back out through the surface.

Formula Properties

Temperature

Warm

Taste Profile

Predominantly acrid and bitter with a mild sweet undertone. The acrid taste disperses and opens the surface, the bitter taste descends Qi and dries Dampness, and the sweetness from Ren Shen and Gan Cao gently supports the Qi.

Target Organs
Lungs Spleen Urinary Bladder Gallbladder
Channels Entered
Lung Bladder Gallbladder Spleen Liver

Formula Origin

Tài Píng Huì Mín Hé Jì Jú Fāng (太平惠民和剂局方)

This is just partial information on the formula's TCM properties. More detailed information is available on the formula's dedicated page

Ingredients in Ren Shen Bai Du San

Detailed information about each herb in Ren Shen Bai Du San and their roles

Kings
Deputies
Assistants
Envoys
Qiang Huo
Qiang Huo

Notopterygium roots

Dosage: 3 - 9g

Temperature Warm
Taste Bitter, Pungent
Organ Affinity Urinary Bladder, Kidneys
Parts Used Dried rhizome and root
Role in Ren Shen Bai Du San

Strongly disperses Wind-Cold from the upper body and exterior, overcomes Dampness, and relieves pain in the head, neck, and upper back. Together with Du Huo, it addresses Wind-Cold-Damp throughout the entire body.

Du Huo
Du Huo

Pubescent angelica roots

Dosage: 3 - 9g

Temperature Warm
Taste Bitter, Pungent
Organ Affinity Urinary Bladder, Kidneys
Parts Used Dried root
Role in Ren Shen Bai Du San

Disperses Wind-Cold-Damp from the lower body and deeper levels, relieving pain in the lower back and legs. Paired with Qiang Huo, the two together treat Wind-Cold-Damp affecting the entire body from head to foot.

Chai Hu
Chai Hu

Bupleurum roots

Dosage: 3 - 9g

Temperature Cool
Taste Bitter
Organ Affinity Gallbladder, Liver
Parts Used Dried root and rhizome
Role in Ren Shen Bai Du San

Releases the exterior through the half-interior/half-exterior level, reduces fever, and raises clear Yang Qi. Assists the King herbs in dispersing pathogenic influences and plays a key role in the formula's ability to address conditions at the Shaoyang level.

Chuan Xiong
Chuan Xiong

Szechuan lovage roots

Dosage: 3 - 9g

Temperature Warm
Taste Pungent
Organ Affinity Gallbladder, Liver, Pericardium
Parts Used Dried rhizome
Role in Ren Shen Bai Du San

Invigorates Blood and moves Qi, dispels Wind, and is especially effective for headache. Assists the King herbs in relieving pain by ensuring smooth circulation of Qi and Blood through the channels.

Jie Geng
Jie Geng

Platycodon roots

Dosage: 3 - 9g

Temperature Neutral
Taste Bitter, Pungent
Organ Affinity Lungs
Parts Used Dried root
Role in Ren Shen Bai Du San

Opens and raises Lung Qi, promotes the expulsion of phlegm, and acts as a 'boat' that directs the formula's actions upward to the chest and Lungs. Paired with Zhi Ke, it restores the Lung's natural rhythm of ascending and descending.

Zhi Ke
Zhi Ke

Bitter oranges

Dosage: 3 - 9g

Temperature Warm
Taste Bitter, Pungent, Sour
Organ Affinity Spleen, Stomach
Parts Used Dried ripe fruit
Role in Ren Shen Bai Du San

Moves Qi downward and broadens the chest, relieving the fullness and stuffiness in the chest and diaphragm. Works with Jie Geng in a classic ascending-descending pair to restore smooth Qi movement.

Qian Hu
Qian Hu

Hogfennel roots

Dosage: 3 - 9g

Temperature Cool
Taste Bitter, Pungent
Organ Affinity Spleen, Lungs
Parts Used Dried root and rhizome
Role in Ren Shen Bai Du San

Directs Lung Qi downward and transforms phlegm, addressing cough with sputum. Also has a mild exterior-releasing action that supports the overall strategy.

Fu Ling
Fu Ling

Poria-cocos mushrooms

Dosage: 3 - 9g

Temperature Neutral
Taste Sweet
Organ Affinity Heart, Kidneys, Lungs, Spleen
Parts Used Dried sclerotium
Role in Ren Shen Bai Du San

Leaches out Dampness through the urine and strengthens the Spleen. Addresses the internal Dampness component of the pattern and supports Ren Shen in tonifying the middle.

Ren Shen
Ren Shen

Ginseng

Dosage: 3 - 9g

Temperature Warm
Taste Bitter, Sweet
Organ Affinity Heart, Lungs, Spleen
Parts Used Dried root
Role in Ren Shen Bai Du San

Tonifies the original Qi to support the body's ability to expel pathogens. This is the formula's signature ingredient: a small dose of Ginseng does not aim to broadly nourish, but rather to give the weakened body just enough Qi to drive out the illness. It also prevents the other dispersing herbs from further depleting the patient's reserves.

Bo He
Bo He

Wild mint

Dosage: 2 - 3g

Temperature Cool
Taste Pungent
Organ Affinity Liver, Lungs
Parts Used Dried aerial parts
Role in Ren Shen Bai Du San

Lightly disperses Wind-Heat from the head and eyes, assists the exterior-releasing herbs, and acts as an envoy to guide the formula toward the body surface.

Sheng Jiang
Sheng Jiang

Fresh ginger

Dosage: 2 - 3g

Temperature Warm
Taste Pungent
Organ Affinity Lungs, Spleen, Stomach
Parts Used Fresh root
Role in Ren Shen Bai Du San

Warms the middle, disperses Cold, and assists in releasing the exterior. Also harmonizes the Stomach to prevent nausea from the other herbs.

Gan Cao
Gan Cao

Liquorice

Dosage: 2 - 6g

Temperature Neutral
Taste Sweet
Organ Affinity Heart, Lungs, Spleen, Stomach
Parts Used Dried root and rhizome
Role in Ren Shen Bai Du San

Harmonizes all the other herbs in the formula, moderates their harsh or dispersing qualities, and mildly tonifies the Spleen Qi together with Ren Shen.

Modern Research (3 studies)

  • Kovir Capsule (based on Ren Shen Bai Du San) in Mild COVID-19: Phase 2 Double-Blind RCT (2022)
  • Network Pharmacology and Molecular Docking Study of RSBDP for Inflammatory Bowel Disease (2022)
See all research on the formula page

Usage & Safety

How to use this formula and important safety information

Important Medical Disclaimer

The information provided here is for educational purposes only and is not intended as medical advice or to replace consultation with a qualified healthcare professional. This formula is a dietary supplement and has not been evaluated by the FDA. It is not intended to diagnose, treat, cure, or prevent any disease.

Always consult with a qualified healthcare provider, particularly if you are pregnant, nursing, have a medical condition, or are taking other medications. Discontinue use and consult your healthcare provider if you experience any adverse reactions.

Recommended Dosage

Instructions for safe storage and consumption

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Best Time to Take

Classically described as 'bu ju shi fu' (not restricted by time), meaning it can be taken whenever needed. In practice, best taken warm between meals, 2-3 times daily. If chills predominate, take hot; if heat signs are present, take warm.

Typical Duration

Acute use: 3-7 days, typically until exterior symptoms resolve. Not intended for long-term use.

Dietary Advice

While taking this formula, avoid cold and raw foods, icy drinks, and greasy or heavy foods, as these can obstruct the Spleen and generate more Dampness, directly counteracting the formula's purpose. Alcohol should be avoided as it generates Damp-Heat internally. Light, warm, easily digestible foods such as plain rice porridge (congee), simple soups, and cooked vegetables are ideal. A small amount of fresh ginger in meals can support the formula's warming, dispersing action. If the formula is being used for early-stage dysentery, avoid dairy products and difficult-to-digest proteins.

Modern Usage

Ren Shen Bai Du San, also known as Shi Wei Tang (Ten-Ingredient Decoction), is a powdered formula made from 10 medicinal ingredients plus Mint and Fresh Ginger. These 10 most important ingredients include Bupleurum (Chai Hu), Licorice (Gan Cao), Platycodon (Jie Geng), and Ginseng (Ren Shen).
It has a pungent and bitter taste and possesses anti-inflammatory, antipyretic (fever-reducing), analgesic (pain-relieving), and liver-protective effects. Clinically, it is used to treat conditions such as acute viral hepatitis and infantile diarrhea.

Special Populations

Pregnancy

Use with caution during pregnancy. The formula contains several acrid, warm, dispersing herbs (Qiang Huo, Du Huo, Chuan Xiong, Chai Hu) that promote the circulation of Qi and Blood. Chuan Xiong in particular is an active Blood-mover and should be used cautiously in pregnancy. Gan Cao (Licorice) may have mild estrogenic and steroid-like effects. While none of the herbs in this formula are classified as strictly prohibited in pregnancy, the overall dispersing and Qi-moving nature of the formula makes it advisable to use only when clearly necessary and under professional guidance. Short-term use for acute illness may be acceptable, but the practitioner should weigh the risks and benefits carefully.

Breastfeeding

No specific contraindication for breastfeeding has been established for this formula. The herbs are generally mild in toxicity. However, the aromatic, acrid, dispersing nature of herbs like Qiang Huo, Du Huo, Chai Hu, and Bo He means that some volatile compounds may theoretically pass into breast milk. Ren Shen (Ginseng) is a stimulant herb that could potentially affect a nursing infant. Gan Cao (Licorice) has mild hormonal activity. Given these considerations, short-term use for acute illness is likely acceptable, but extended use should be avoided. A practitioner should be consulted to weigh the benefit of treating the mother's acute condition against any theoretical risk to the infant.

Pediatric Use

This formula was originally designed for pediatric use, since children's Qi is naturally immature and they are prone to exterior invasions that their bodies cannot fully expel. Classical texts note that because children's constitutional Qi is underdeveloped, the small amount of Ren Shen in the formula is especially appropriate for them. Dosage should be adjusted by age: as a general guideline, newborns receive approximately 1/6 of the adult dose, infants and toddlers receive 1/3 to 1/2, and older children receive 1/2 to 2/3 of the adult dose. The formula is considered appropriate for pediatric respiratory infections, infantile diarrhea, and childhood skin eruptions with exterior Cold-Damp signs. A qualified practitioner should supervise use in young children.

Drug Interactions

Gan Cao (Licorice): This formula contains Gan Cao, which has several well-documented drug interactions. Licorice may reduce the effectiveness of warfarin (an anticoagulant), potentially increasing clotting risk. It can enhance the side effects of corticosteroids by potentiating their mineralocorticoid activity, possibly causing fluid retention, elevated blood pressure, and low potassium. It may also interact with digoxin (a heart medication) by causing potassium depletion, which increases the risk of digoxin toxicity. People taking certain diuretics (especially potassium-wasting types like thiazides or loop diuretics) should be cautious, as the combination could worsen potassium loss. Gan Cao may also have weak MAO-inhibitor-like activity.

Ren Shen (Ginseng): Ginseng may interact with MAO-inhibitor antidepressants (such as phenelzine), potentially causing headache, tremor, or mania. It may also affect blood sugar levels, which is relevant for people taking insulin or oral diabetes medications. Ginseng should ideally be discontinued at least one week before surgery due to its potential effects on bleeding and blood pressure.

Chai Hu (Bupleurum) and Chuan Xiong (Ligusticum): Both herbs may have mild antiplatelet activity. Patients taking anticoagulant or antiplatelet drugs (warfarin, aspirin, clopidogrel) should use this formula with caution, as there may be an additive effect on bleeding risk.

Contraindications

Avoid

External Wind-Heat patterns or Yin-deficient exterior conditions. The formula is predominantly warm, acrid, and drying, making it inappropriate when Heat signs predominate.

Avoid

Dysentery caused by Damp-Heat or Summer-Heat steaming in the intestines. Classical sources explicitly warn that this formula must not be used for dysentery of a purely Hot or Damp-Heat nature without exterior Cold signs.

Avoid

Patients without genuine exterior Wind-Cold-Damp signs (no chills, no body aches, no absence of sweating). The formula is only indicated when exterior Cold-Damp is confirmed.

Caution

Patients with significant Yin deficiency or Blood deficiency. The acrid, warm, dispersing herbs can further consume Yin and fluids.

Caution

Patients who are sweating profusely or have already broken into a sweat. The strong exterior-releasing action may over-disperse and damage Qi and fluids.

Cautions & Warnings

Although this formula is typically safe for most individuals, it may cause side effects in some people. Pregnant women, nursing mothers, postpartum women, and those with liver disease should use the formula with caution.

As with any Chinese herbal remedy, it is advisable to seek guidance from a qualified TCM practitioner before beginning treatment.

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