Zhu Jing Wan

Vision-Preserving Pill · 驻景丸

A classical three-herb pill that strengthens the Liver and Kidneys, nourishes the blood and essence, and sharpens eyesight. It is traditionally used for declining vision, blurry sight, floaters, and dark shadows in front of the eyes caused by deficiency of the Liver and Kidneys.

Origin Tai Ping Sheng Hui Fang (太平圣惠方), Volume 33 — Northern Song dynasty, ~992 CE
Composition 3 herbs
Tu Si Zi
King
Tu Si Zi
Shu Di Huang
Deputy
Shu Di Huang
Che Qian Zi
Assistant / Envoy
Che Qian Zi
Explore composition

Educational content Consult qualified TCM practitioners for diagnosis and treatment

Patterns Addressed

In TCM, symptoms don't appear randomly — they cluster into recognizable patterns of disharmony that reveal what's out of balance in the body. Zhu Jing Wan is designed to correct these specific patterns.

Why Zhu Jing Wan addresses this pattern

This pattern is the underlying reason for visual decline in the classical indication of “Liver and Kidney both deficient, eyes habitually dim.” The formula’s Tu Si Zi and Shu Di Huang directly replenish Liver blood and Kidney yin, while Che Qian Zi ensures the nourishment is not hindered by stagnant dampness or residual heat. The result is that the core deficiency is corrected and the eyes receive the blood and essence they need to see clearly.

A practitioner would look for one or more of these signs

Blurred Vision

Gradual loss of visual clarity; objects appear hazy

Floaters

Dark specks or threads moving across the field of vision

Dry Eyes

Sensation of grittiness or insufficient moisture

Night Blindness

Difficulty seeing in low light or at night

Photophobia

Sensitivity to bright light

Tinnitus

Ringing in the ears, often accompanying visual weakness

Commonly Prescribed For

These conditions can arise from the patterns above. A practitioner would consider Zhu Jing Wan when these conditions are specifically caused by those patterns — not for all cases of these conditions.

TCM Interpretation

Age‑related macular degeneration is seen as a decline of Liver and Kidney essence and blood. The macula, responsible for central vision, depends on the nourishment of Kidney essence and Liver blood. Over time, deficient yin and essence lead to accumulation of metabolic waste (phlegm‑dampness) and the appearance of drusen. This formula addresses the root by rebuilding essence and blood, which in turn helps clear the waste from the retina.

Why Zhu Jing Wan Helps

Tu Si Zi and Shu Di Huang directly restore Liver and Kidney yin, while Che Qian Zi helps clear dampness that otherwise obstructs the delicate retinal tissues. Clinical studies show that modified versions of this formula improve visual acuity, reduce drusen area, and enhance antioxidant enzyme activity in dry AMD patients. The simple foundation of Zhu Jing Wan provides a base for adding herbs that target phlegm and stasis as needed.

Also commonly used for

Cataracts (Early Stage)

Replenishes essence to delay lens opacification and improve clarity

Central Serous Chorioretinopathy

Supports retinal pigment epithelium function through yin and blood nourishment

Retinitis Pigmentosa

Slows progression by tonifying the fundamental deficiency of Liver and Kidney essence

Optic Nerve Atrophy

Provides deep yin and blood support to preserve remaining nerve function

Dry Eye Syndrome

Moistens and nourishes the eyes by addressing the root yin deficiency

Visual Fatigue (Asthenopia)

Alleviates eye strain and blurriness from prolonged close work when due to deficiency

Myopia (Progressive)

Used as a constitutional tonic to slow elongation of the globe in children and adolescents

What This Formula Does

Every TCM formula has a specific set of actions — here's what Zhu Jing Wan does in the body, explained in both everyday and TCM terms

Therapeutic focus

In practical terms, Zhu Jing Wan is primarily used to support these areas of health:

TCM Actions

In TCM terminology, these are the specific therapeutic actions that Zhu Jing Wan performs to restore balance in the body:

How It Addresses the Root Cause

TCM doesn't just suppress symptoms — it aims to resolve the underlying imbalance. Here's how Zhu Jing Wan works at the root level.

The eyes are the “orifice” of the Liver and depend on Liver blood and Kidney essence for clear vision. When the Liver and Kidneys become depleted—whether through aging, overwork, chronic illness, or excessive use of the eyes—the essence and blood fail to ascend to the head. This leads to visual decline: blurry sight, dark spots or floaters, poor night vision, and a sensation of a veil over the eyes. The root is a deficiency of the yin, blood, and essence of the Liver and Kidneys, with the eyes as the main site of manifestation. This formula replenishes that core deficiency and specifically directs nourishment upward to brighten the vision.

Formula Properties

Every formula has an inherent temperature, taste, and affinity for specific organs — these properties determine how it interacts with the body

Overall Temperature

Neutral

Taste Profile

Predominantly sweet — sweet to nourish and tonify, with a subtle bland-cool aspect from Che Qian Zi to prevent stagnation and gently clear heat.

Target Organs

Channels Entered

Liver Kidney

Ingredients

3 herbs

The herbs that make up Zhu Jing Wan, organized by their role in the prescription

King — Main ingredient driving the formula
Deputy — Assists and enhances the King
King — Main ingredient driving the formula
Tu Si Zi

Tu Si Zi

Chinese Dodder Seed

Dosage 9 - 12g (decoction); 150g (pill batch)
Temperature Neutral
Taste Acrid / Pungent (辛 xīn), Sweet (甘 gān)
Organ Affinity Liver, Kidneys, Spleen

Role in Zhu Jing Wan

Tonifies both the yin and the yang of the Liver and Kidneys, directly brightens the eyes, and anchors the essence. Its balanced, gentle nature makes it the central ingredient for treating visual weakness due to deficiency.
Deputy — Assists and enhances the King
Shu Di Huang

Shu Di Huang

Prepared Rehmannia root

Dosage 9 - 15g (decoction); 90g (pill batch)
Temperature Slightly Warm
Taste Sweet (甘 gān)
Organ Affinity Liver, Kidneys

Role in Zhu Jing Wan

Richly nourishes Kidney yin and blood, fills the essence, and strengthens the foundation of the Liver and Kidneys, so that the eyes are properly moistened and nourished.

Why This Combination Works

How the herbs in Zhu Jing Wan complement each other

Overall strategy

The formula addresses Liver and Kidney deficiency that impairs vision. It pairs a gentle tonic herb with a substance that fills the essence and a clearing herb that guides the action to the eyes, making a simple but precise formula for chronic visual weakness.

King herb

Tu Si Zi (菟丝子) is the king. It tonifies both yin and yang of the Liver and Kidneys, nourishes the essence, and has a specific affinity for the eyes. It is the primary herb for gradually restoring clear sight.

Deputy herb

Shu Di Huang (熟地黄) reinforces the king by providing deep, rich nourishment to Kidney yin and blood. It fills the essence storehouse so that the eyes receive lasting support.

Assistant herb

Che Qian Zi (车前子) serves as both an assistant and an envoy. It clears liver heat and promotes urination, drawing excess fire downward and allowing the tonifying herbs to work without causing stagnation. Its downward and outward direction helps guide the nourishing action specifically to the eyes.

How to Prepare

Traditional preparation instructions for Zhu Jing Wan

The three herbs are ground into a fine powder, mixed with honey to form pills the size of wutong seeds. The original recipe calls for Tu Si Zi 150g, Che Qian Zi 30g, and Shu Di Huang 90g to make a batch of pills. Take about 9 g (roughly 30 pills) per dose on an empty stomach, with warm wine or a mild salt decoction. A second dose can be taken before the evening meal. In modern practice the formula may also be decocted, with daily doses of Tu Si Zi 9–12g, Shu Di Huang 9–15g, and Che Qian Zi 9–12g (wrapped in cloth).

Common Modifications

How practitioners adapt Zhu Jing Wan for specific situations

Added
Dang Gui

Add 6–9 g to nourish Liver blood

Bai Shao

Add 6–12 g to astringe yin and soften the Liver

Dang Gui and Bai Shao strengthen the blood‑nourishing action of the formula, making it more suitable when signs of blood deficiency are prominent.

Educational content — always consult a qualified healthcare provider or TCM practitioner before using any herbal formula.

Contraindications

Situations where Zhu Jing Wan should not be used or requires extra caution

Avoid

Pregnancy and breastfeeding. The formula's safety during pregnancy and lactation has not been established; some components may affect fetal development or milk secretion.

Caution

Damp-heat or phlegm-dampness patterns with greasy tongue coating, heaviness, and digestive symptoms. The tonifying nature may worsen dampness.

Caution

Spleen deficiency with loose stools or diarrhea. Che Qian Zi (Plantain Seed) may exacerbate loose stools.

Caution

Acute inflammatory eye diseases with redness, swelling, and pain. Tonification may trap the pathogen.

Special Populations

Important considerations for pregnancy, breastfeeding, and pediatric use

Pregnancy

Contraindicated during pregnancy. Although Tu Si Zi (Cuscuta) is sometimes used in small, carefully monitored doses for threatened miscarriage in other formulas, the overall composition and dosage of this formula are considered unsafe during pregnancy. Avoid use unless under strict professional supervision where deemed absolutely necessary.

Breastfeeding

No specific data on breast milk transfer exists for the herbs in this formula. Caution is advised during breastfeeding. Use only under professional guidance; some components may affect milk composition or the nursing infant.

Children

Not typically prescribed for children. If used in adolescents for myopia or other conditions, dosage must be significantly reduced and treatment overseen by a pediatric TCM specialist. The formula is primarily designed for age-related visual decline and may not be appropriate for most pediatric eye conditions.

Drug Interactions

If you are taking pharmaceutical medications, be aware of these potential interactions with Zhu Jing Wan

No well-documented drug interactions. Consult a healthcare provider before concurrent use with prescription medications.

Usage Guidance

Practical advice for getting the most out of Zhu Jing Wan

Best time to take

Take on an empty stomach (at least 30 minutes before meals), once in the morning and once before the evening meal. Traditionally taken with warm rice wine or lightly salted water to guide the herbs to the Kidneys.

Typical duration

Typically prescribed for 8–12 weeks, with reassessment after 4 weeks. Long-term use should be monitored for any digestive side effects.

Dietary advice

Avoid cold, raw, and difficult-to-digest foods while taking this tonic formula to protect Spleen function and prevent dampness. Limit greasy, fried, and spicy foods. The classical preparation uses warm wine or salt water as a vehicle; however, heavy alcohol consumption beyond the medicinal use should be avoided.

Zhu Jing Wan originates from Tai Ping Sheng Hui Fang (太平圣惠方), Volume 33 Northern Song dynasty, ~992 CE

Classical Texts

Key passages from the classical Chinese medical texts that first described Zhu Jing Wan and its clinical use

Original source — Tai Ping Sheng Hui Fang, Volume 33:
“治肝肾俱虚,眼常昏暗,多见黑花,或生障翳,视物不明,迎风流泪。久服补肝肾,增目力。”
(“Treats dual deficiency of Liver and Kidneys, where the eyes are habitually dim, often seeing black spots, possibly producing cataracts or opacities, vision unclear, tearing when facing wind. Long-term use supplements Liver and Kidneys and sharpens vision.”)

Ben Cao Gang Mu, Chapter on Che Qian:
“补虚明目(肝肾均虚,眼发黑花,或生障翳,迎风流泪)… 驻景丸。”
(“Tonifies deficiency and brightens the eyes — for cases where both Liver and Kidneys are deficient, the eyes produce black spots, or cataracts develop, with tearing when facing wind… this is Dwelling Light Pill.”)

Historical Context

How Zhu Jing Wan evolved over the centuries — its origins, lineage, and place in the broader tradition of Chinese medicine

The original Dwelling Light Pill (Zhu Jing Wan) appears in the Northern Song dynasty compendium Tai Ping Sheng Hui Fang (~992 CE), a massive government-sponsored medical encyclopedia. Its elegant name, “Dwelling Light” (驻景), suggests that by tonifying the Liver and Kidneys the formula enables the world’s scenery to remain clear in the eyes — a poetic reflection of its aim to preserve sight.

Over centuries, the formula was modified. The Yin Hai Jing Wei (《银海精微》) added more blood- and essence-nourishing herbs like Gou Qi Zi, Chu Shi Zi, and Wu Wei Zi. In the 20th century, the renowned ophthalmologist Chen Dafu (陈达夫) further expanded it in his Zhong Yi Yan Ke Liu Jing Fa Yao to address complex, mixed deficiency-excess eye diseases such as macular degeneration and diabetic retinopathy. Today, both the original three-herb formula and its later variants remain fundamental tools in TCM ophthalmology.

Modern Research

A published study investigating the pharmacological effects or clinical outcomes of Zhu Jing Wan

1

A randomized controlled trial of modified Zhujing Pills for dry age-related macular degeneration (2024)

Feng SQ, Zhou X, Zhang YZ, et al. Clinical Study on the Treatment of Dry Age-Related Macular Degeneration of Liver and Kidney Insufficiency Type with Modified Zhujing Pills. J Nanjing Univ Tradit Chin Med. 2024;40(5):521-526.

In a 64-patient RCT (32 per arm), patients with dry age-related macular degeneration of the Liver-Kidney insufficiency type received either modified Zhujing Pills granules or a control treatment for 3 months. The Zhujing Pill group showed significantly improved visual acuity, reduced drusen area, decreased fundus autofluorescence intensity, and increased plasma SOD and GSH-Px activities, with reduced MDA levels. The therapeutic mechanism may involve activation of the Nrf2/Keap1 antioxidant pathway.

DOI

Research on TCM formulas is growing but still limited by Western clinical trial standards. These studies provide emerging evidence and should be considered alongside practitioner expertise.