Yu Lu San

Jade Dew Powder · 玉露散

Also known as: Gan Lu Yin (甘露饮, Sweet Dew Drink), Yu Lu Yin (玉露饮, Jade Dew Drink)

A simple but powerful cooling formula from Song Dynasty pediatric medicine, designed to quickly clear internal Heat that causes vomiting, diarrhea, fever, and irritability in children. It combines two cold mineral substances (Gypsum and Glauberite) with Licorice root to bring down high temperatures and calm the digestive system, and is also used for heatstroke with thirst and restlessness.

Origin Xiao Er Yao Zheng Zhi Jue (小儿药证直诀) by Qian Yi (钱乙), compiled by Yan Xiaozhong (阎孝忠) — Northern Song dynasty, compiled 1119 CE
Composition 3 herbs
Shi Gao
King
Shi Gao
Han Shui Shi
Deputy
Han Shui Shi
Gan Cao
Envoy
Gan Cao
Explore composition

Educational content Consult qualified TCM practitioners for diagnosis and treatment

Patterns Addressed

In TCM, symptoms don't appear randomly — they cluster into recognizable patterns of disharmony that reveal what's out of balance in the body. Yu Lu San is designed to correct these specific patterns.

Why Yu Lu San addresses this pattern

When Heat accumulates in the Stomach, it disrupts the organ's ability to "rot and ripen" food and direct its contents downward. Instead, food and fluids rebel upward as vomiting and pour downward as watery diarrhea. The child develops fever, irritability, thirst, and restlessness. Yu Lu San directly addresses this by deploying Shi Gao to clear Yangming Stomach Heat and Han Shui Shi to cool the associated Heat in deeper channels. Raw Gan Cao protects the Stomach lining from the cold minerals while contributing its own mild Heat-clearing action. The formula restores normal downward movement in the Stomach and stops the vomiting and diarrhea at their root.

A practitioner would look for one or more of these signs

Vomiting

Vomiting of undigested milk or food due to Stomach Heat

Diarrhea

Diarrhea with deep yellow stools

Fever

High fever with body heat

Irritability

Restlessness and irritability in children

Thirst

Intense thirst with desire to drink

Commonly Prescribed For

These conditions can arise from the patterns above. A practitioner would consider Yu Lu San when these conditions are specifically caused by those patterns — not for all cases of these conditions.

Arises from: Stomach Heat

TCM Interpretation

In TCM, acute gastroenteritis in children is most commonly understood as Heat or Dampness-Heat accumulating in the Stomach and Intestines. When the predominant factor is Heat (rather than Dampness), the child presents with strong fever, irritability, thirst, vomiting of undigested food, and diarrhea with yellow, foul-smelling stools. The Stomach loses its normal descending function, and the Spleen loses its normal ascending and transporting function. The key diagnostic distinction is that this is a Heat-dominant pattern: the child feels hot to the touch, is restless rather than listless, and the stools are yellow rather than white or watery.

Why Yu Lu San Helps

Yu Lu San directly targets the Heat at the root of this condition. Shi Gao clears the blazing Stomach Heat that is driving the vomiting, while Han Shui Shi extends the cooling action deeper to stop the Heat-driven diarrhea. Raw Gan Cao protects the already-stressed digestive lining from the cold nature of the minerals. The formula is specifically designed for the pediatric digestive system, using a minimal number of ingredients at appropriate doses. By clearing Heat quickly, it allows the Stomach and Spleen to resume their normal coordinated movement, stopping both vomiting and diarrhea simultaneously.

Also commonly used for

Vomiting

Heat-related vomiting in children

Diarrhea

Acute diarrhea from internal Heat or summerheat

Fever

High fever in children, especially from summerheat

Heat Rash

Heat rash (prickly heat) in infants and children

What This Formula Does

Every TCM formula has a specific set of actions — here's what Yu Lu San does in the body, explained in both everyday and TCM terms

Therapeutic focus

In practical terms, Yu Lu San is primarily used to support these areas of health:

TCM Actions

In TCM terminology, these are the specific therapeutic actions that Yu Lu San performs to restore balance in the body:

How It Addresses the Root Cause

TCM doesn't just suppress symptoms — it aims to resolve the underlying imbalance. Here's how Yu Lu San works at the root level.

This formula addresses a pattern in which Heat accumulates in the interior of the body, particularly in the Stomach and Intestines. In TCM pediatric theory, children's organ systems are described as "delicate and immature" (脏腑柔弱), meaning they are easily overwhelmed by either Heat or Cold. When a child is exposed to summerheat or consumes food that generates internal Heat (such as overheating breast milk or rich foods), the Stomach and Spleen can become overloaded with Heat.

When this Heat blazes in the Yangming (Stomach channel), it disrupts the Stomach's normal downward-directing function and the Spleen's upward-transporting function. The result is that food and fluids "rebel" in both directions: upward as vomiting and downward as diarrhea, often with deep yellow stools. The internal Heat also agitates the spirit, causing irritability and restlessness, and consumes body fluids, causing thirst and fever. In severe cases involving summerheat, the Heat can cloud the mind, leading to drowsiness or even loss of consciousness.

The underlying logic is straightforward: excessive Heat in the middle and upper body needs to be cleared directly with cold, heavy mineral substances that can rapidly quench the fire and restore normal digestive function. Because the child's body is inherently prone to rapid changes between Heat and Cold, the formula uses strong but simple mineral cooling rather than complex herbal strategies.

Formula Properties

Every formula has an inherent temperature, taste, and affinity for specific organs — these properties determine how it interacts with the body

Overall Temperature

Cold

Taste Profile

Predominantly bland and slightly sweet with a mineral, salty quality — cool and heavy in character, designed to settle heat and calm restlessness.

Channels Entered

Stomach Lung Heart Kidney

Ingredients

3 herbs

The herbs that make up Yu Lu San, organized by their role in the prescription

King — Main ingredient driving the formula
Deputy — Assists and enhances the King
Envoy — Directs the formula to its target
King — Main ingredient driving the formula
Shi Gao

Shi Gao

Gypsum

Dosage 15g
Temperature Cold
Taste Acrid / Pungent (辛 xīn), Sweet (甘 gān)
Organ Affinity Lungs, Stomach

Role in Yu Lu San

Shi Gao is acrid, sweet, and very cold, entering the Lung and Stomach channels. As the primary Heat-clearing mineral in the formula, it powerfully clears blazing Heat from the Yangming (Stomach) channel, relieves irritability, and generates fluids to address the thirst and high fever at the core of this pattern.
Deputy — Assists and enhances the King
Han Shui Shi

Han Shui Shi

Calcite (or Red Gypsum)

Dosage 15g
Temperature Cold
Taste Acrid / Pungent (辛 xīn), Salty (咸 xián)
Organ Affinity Heart, Stomach, Kidneys

Role in Yu Lu San

Han Shui Shi is acrid, salty, and cold, entering the Heart, Stomach, and Kidney channels. It strongly reinforces the Heat-clearing action of Shi Gao while also directing cooling power into the Shaoyin (Kidney) channel, helping to stop vomiting and diarrhea caused by internal Heat. Its salty nature aids in drawing Heat downward and out of the body.
Envoy — Directs the formula to its target
Gan Cao

Gan Cao

Licorice root

Dosage 3g
Temperature Neutral
Taste Sweet (甘 gān)
Organ Affinity Heart, Lungs, Spleen, Stomach

Role in Yu Lu San

Raw Gan Cao (used unprocessed) clears residual Heat and harmonizes the Stomach, protecting the delicate digestive system of children from the harsh cold nature of the two mineral herbs. It also moderates and unifies the actions of the formula.

Why This Combination Works

How the herbs in Yu Lu San complement each other

Overall strategy

The formula uses two powerful Heat-clearing minerals paired with a single harmonizing herb to rapidly clear internal Heat from the Stomach and Intestines, restore normal digestive movement, and protect the child's delicate digestion from the harshness of the cold minerals. It is deliberately simple and direct, reflecting Qian Yi's principle of treating pediatric conditions with streamlined, targeted prescriptions.

King herbs

Shi Gao (Gypsum) serves as the King herb. It is acrid, sweet, and very cold, and has a special affinity for the Yangming (Stomach) channel. It powerfully clears blazing Stomach Heat, relieves the irritability and restlessness caused by internal fire, and generates fluids to address thirst. Its sweet flavor also gently supports the Stomach rather than damaging it.

Deputy herbs

Han Shui Shi (Glauberite/Mirabilite crystal) complements Shi Gao by adding a salty, cold dimension. While Shi Gao focuses on the Yangming, Han Shui Shi extends the cooling action to the Shaoyin (Kidney) channel as well. Its salty quality helps draw Heat downward and out through the waterways, specifically helping to stop the vomiting and diarrhea driven by Heat disrupting the digestive organs.

Envoy herbs

Raw Gan Cao (Licorice root, unprocessed) serves dual functions: it gently clears Heat in its own right and, crucially, it harmonizes and protects the Stomach from the intensely cold nature of the two mineral herbs. In a pediatric formula, this protective role is essential because children's digestive systems are easily damaged by excessive cold. Gan Cao also helps unify the actions of the two minerals into a coherent therapeutic effect.

Notable synergies

The pairing of Shi Gao and Han Shui Shi is a classic mineral combination for clearing Heat. Shi Gao targets the Yangming while Han Shui Shi reaches the Shaoyin, together covering a broader range of Heat pathology than either could alone. Their combined effect is more powerful for stopping Heat-driven vomiting and diarrhea than a single mineral used at higher dosage.

How to Prepare

Traditional preparation instructions for Yu Lu San

Grind all three ingredients together into a very fine powder (xi mo, 细末). This is a powder formula (san ji, 散剂), not a decoction.

Dosage and administration: Each dose ranges from approximately 1 to 3 grams (the classical text specifies "one zi, half a qian, or one qian," roughly 0.3 to 3 grams, adjusted by the child's age and condition). Mix the powder into warm water and take after meals. The classical text specifically notes that Han Shui Shi should be the soft, slightly blue-black variety with fine lines, and that Shi Gao should be the firm, white, layered mineral that cannot be broken by hand. Careful identification of these two minerals is essential, as the text itself warns that southern and northern regions sometimes confuse the two.

Common Modifications

How practitioners adapt Yu Lu San for specific situations

According to the Xiao Er Yao Zheng Zhi Jue, when Heat predominates (as in the fifth lunar month), Yu Lu San is used as the sole formula, taken after meals. No additions are needed as the base formula is sufficient.

Educational content — always consult a qualified healthcare provider or TCM practitioner before using any herbal formula.

Contraindications

Situations where Yu Lu San should not be used or requires extra caution

Avoid

Spleen and Stomach deficiency cold (脾胃虚寒): Both Han Shui Shi and Shi Gao are very cold in nature and will worsen symptoms in anyone whose digestive system is already cold and weak, such as those with chronic loose stools, poor appetite, cold limbs, and a pale tongue with white coating.

Avoid

Yin deficiency with internal heat (阴虚火旺): This formula clears excess Heat only. It should not be used when the heat arises from depleted Yin fluids, as the intensely cold minerals can further damage Yin and injure the Stomach without addressing the root cause.

Avoid

Diarrhea or vomiting from cold (寒证吐泻): If vomiting and diarrhea are caused by cold invading the Spleen and Stomach rather than internal Heat, this formula will dramatically worsen the condition. The original text specifies this formula only for cases where Heat is the underlying cause.

Caution

Constitutionally weak or deficient patients: Classical sources warn that Han Shui Shi is contraindicated for 'deficient people with floating heat' (虚人热浮). Use with extreme caution in frail children or those recovering from prolonged illness.

Caution

Prolonged or excessive use: Both Han Shui Shi and Shi Gao are heavy, cold minerals that can injure the Spleen and Stomach with extended use. This formula is intended for short-term, acute conditions only.

Special Populations

Important considerations for pregnancy, breastfeeding, and pediatric use

Pregnancy

Generally not applicable, as Yu Lu San was designed specifically for pediatric use. However, its extremely cold nature (containing two heavy, cold minerals) makes it inadvisable during pregnancy. The intensely cold properties of Han Shui Shi and Shi Gao could injure the Spleen and Stomach, potentially affecting the mother's digestive function and nutritional absorption. Pregnant women experiencing heat conditions should use milder alternatives under professional guidance.

Breastfeeding

Yu Lu San is a pediatric formula typically given directly to the child, not to a breastfeeding mother. If a nursing mother were to take it, the intensely cold mineral ingredients (Han Shui Shi and Shi Gao) could theoretically cool the Stomach and reduce appetite, potentially affecting milk production. Nursing mothers with heat conditions should consult a practitioner for more appropriate formulas. When the formula is given directly to a breastfeeding infant, only very small doses should be used and only under professional supervision.

Children

Yu Lu San was specifically designed for pediatric use and is one of the signature formulas from the earliest surviving Chinese pediatric textbook. Classical dosing is weight- and age-dependent: - Infants and toddlers: approximately 0.3–1 gram per dose - Children aged 3–6: approximately 1–3 grams per dose The powder is mixed into warm water and given after meals. Because both Han Shui Shi and Shi Gao are intensely cold minerals, this formula should only be used for confirmed heat patterns (fever, irritability, thirst, yellow diarrhea) and discontinued as soon as symptoms resolve. Prolonged use risks damaging the child's delicate Spleen and Stomach function. The original author Qian Yi emphasized that children's organs are 'easily made deficient, easily made excessive, easily made cold, easily made hot,' so careful monitoring during treatment is essential.

Drug Interactions

If you are taking pharmaceutical medications, be aware of these potential interactions with Yu Lu San

No well-documented pharmaceutical drug interactions have been established for Yu Lu San specifically. However, based on the pharmacological properties of its mineral ingredients, the following theoretical considerations apply:

  • Calcium-containing medications and supplements: Both Shi Gao (calcium sulfate) and Han Shui Shi (calcium carbonate or calcium sulfate, depending on regional variety) are calcium-rich minerals. Concurrent use with calcium supplements, antacids, or calcium channel blockers should be approached with caution, as excessive calcium intake may occur.
  • Medications affected by gastric pH: The mineral components may alter gastric acidity, potentially affecting the absorption of drugs that require specific pH conditions (such as certain antibiotics or antifungals). It is prudent to separate administration by at least two hours.
  • Digoxin and cardiac glycosides: Gan Cao (Glycyrrhiza, licorice) can cause potassium loss with prolonged use, which may increase sensitivity to digoxin. However, at the very small doses used in Yu Lu San, this risk is minimal.

Usage Guidance

Practical advice for getting the most out of Yu Lu San

Best time to take

After meals (食后), mixed into warm water, as specified in the original text.

Typical duration

Acute use only: 1–3 days, discontinued as soon as heat symptoms (fever, irritability, yellow diarrhea) resolve.

Dietary advice

While taking Yu Lu San, avoid foods that generate internal heat or are difficult to digest. Specifically: - Avoid greasy, fried, and spicy foods, which add heat and burden the Stomach - Avoid excessively sweet or rich foods that may cause food stagnation - Favor easily digestible, bland foods such as rice congee and clear soups - Because the formula is very cold in nature, avoid adding cold or raw foods simultaneously, as this could over-chill the Stomach - Ensure adequate fluid intake, as febrile children are prone to dehydration

Yu Lu San originates from Xiao Er Yao Zheng Zhi Jue (小儿药证直诀) by Qian Yi (钱乙), compiled by Yan Xiaozhong (阎孝忠) Northern Song dynasty, compiled 1119 CE

Classical Texts

Key passages from the classical Chinese medical texts that first described Yu Lu San and its clinical use

From the Xiao Er Yao Zheng Zhi Jue (小儿药证直诀), 'Summer-Autumn Vomiting and Diarrhea' section:

「五月十五日以后,吐泻,身壮热,此热也……或因伤热乳食,吐乳不消,泻深黄色,玉露散主之。」

Translation: "After the fifteenth day of the fifth month, if there is vomiting and diarrhea with strong bodily heat, this is due to Heat... or if caused by damage from hot breast milk or food, with undigested milk being vomited and deep yellow diarrhea, Yu Lu San governs this."


From the same section, on seasonal treatment:

「六月十五日以后,吐泻,身温似热……食前少服益黄散,食后多服玉露散。」

Translation: "After the fifteenth day of the sixth month, if there is vomiting and diarrhea with the body warm as if feverish... take a small dose of Yi Huang San before meals and a larger dose of Yu Lu San after meals."


Original formula entry in the Xiao Er Yao Zheng Zhi Jue, lower volume:

「寒水石(软而微青黑,中有细纹者是)石膏(坚白而墙壁手不可折者是好,各半两)甘草(生一钱)上同为细末,每服一字或半钱、壹钱,食后,温汤调下。」

Translation: "Han Shui Shi (the soft, slightly blue-black kind with fine lines is correct), Shi Gao (the firm, white kind with layered structure that cannot be broken by hand is best, half a liang each), raw Gan Cao (one qian). Grind all together into fine powder. Each dose is one zi, half a qian, or one qian, taken after meals, mixed into warm water."

Historical Context

How Yu Lu San evolved over the centuries — its origins, lineage, and place in the broader tradition of Chinese medicine

Yu Lu San was created by Qian Yi (钱乙, c. 1032–1113), the most celebrated pediatric physician in Chinese medical history, often called the "Sage of Pediatrics" (儿科之圣). The formula appears in his masterwork, the Xiao Er Yao Zheng Zhi Jue (小儿药证直诀, "Key to Diagnosis and Treatment of Children's Diseases"), which was compiled posthumously by his student Yan Xiaozhong (阎孝忠) in 1119 CE. This book is recognized as the world's earliest surviving pediatric monograph in its original form.

The formula reflects Qian Yi's characteristic approach to children's illnesses: simple compositions using gentle yet effective strategies. His principle that children's organs are "formed but not yet complete, complete but not yet strong" (成而未全,全而未壮) led him to favor straightforward formulas. Yu Lu San exemplifies this, using just three substances to clear internal heat from the Stomach while protecting digestive function. The text also contains an important pharmaceutical note distinguishing Han Shui Shi from Shi Gao, warning that southern and northern regions often confused these two minerals, a mix-up that could lead to clinical errors, especially dangerous in children.

The formula also carries the alternate names Gan Lu Yin (甘露饮) in the same text and Yu Lu Yin (玉露饮) in the later work Huo You Xin Shu (活幼新书). Its name, "Jade Dew Powder," poetically evokes the image of cool, precious dew bringing relief from scorching heat, fitting for a formula that clears summer heat and calms irritability in feverish children.