Qi Ge San

Open the Diaphragm Powder · 啟膈散

Also known as: 启膈散

A classical formula for difficulty swallowing and food getting stuck in the throat or chest, often with belching, dry mouth, and gradual weight loss. It works by moistening dryness, moving stagnant Qi, and dissolving Phlegm that has become lodged in the esophagus and diaphragm area.

Origin Yi Xue Xin Wu (《医学心悟》Medical Revelations), Volume 3, by Cheng Guopeng (程国彭) — Qīng dynasty, 1732 CE
Composition 8 herbs
Bei Sha Shen
King
Bei Sha Shen
Chuan Bei Mu
Deputy
Chuan Bei Mu
Dan Shen
Deputy
Dan Shen
Yu Jin
Assistant
Yu Jin
Fu Ling
Assistant
Fu Ling
Sha Ren
Assistant
Sha Ren
He Ye
Envoy
He Ye
Mi Pi Kang
Envoy
Mi Pi Kang
Explore composition
Available in our store
View in Store
From $105.00

Educational content Consult qualified TCM practitioners for diagnosis and treatment

Patterns Addressed

In TCM, symptoms don't appear randomly — they cluster into recognizable patterns of disharmony that reveal what's out of balance in the body. Qi Ge San is designed to correct these specific patterns.

Why Qi Ge San addresses this pattern

In this pattern, Qi becomes stuck in the chest and diaphragm region, leading to a sense of obstruction and difficulty swallowing. Over time, stagnant Qi dries out body fluids and generates Phlegm, creating a vicious cycle where the passages become increasingly blocked. Qi Ge San addresses this by using Yu Jin and Sha Ren Ke to move the stagnant Qi, while Bei Sha Shen regenerates lost fluids and Chuan Bei Mu dissolves the resulting Phlegm. The formula's balanced ascending and descending actions (He Ye Di lifts, Chu Tou Kang descends) restore the normal directional flow of Qi through the diaphragm.

A practitioner would look for one or more of these signs

Difficulty In Moving

Food feels stuck in the throat or chest when swallowing

Chest Distension

Fullness and distension in the chest and diaphragm area, relieved by belching

Belching

Frequent belching that temporarily eases the chest discomfort

Dry Mouth

Dry mouth and throat due to Qi stagnation consuming fluids

Epigastric Fullness And Pain Relieved By Vomiting

Dry retching or vomiting of mucus/saliva

Commonly Prescribed For

These conditions can arise from the patterns above. A practitioner would consider Qi Ge San when these conditions are specifically caused by those patterns — not for all cases of these conditions.

TCM Interpretation

TCM understands chronic swallowing difficulty (ye ge, 噎膈) as a condition rooted in the diaphragm and esophagus where multiple pathogenic factors converge. Emotional strain or prolonged stress causes Liver Qi to stagnate, which then affects the Stomach and Spleen's ability to transport and transform. Over time, this stagnation generates Phlegm, consumes body fluids (leading to dryness), and eventually produces Blood stasis. The result is a progressive obstruction where food cannot pass smoothly through the esophagus and chest area. The condition typically involves the Liver (emotional stagnation), Stomach (descending function impaired), and Spleen (Phlegm production).

Why Qi Ge San Helps

Qi Ge San addresses all the interlocking factors behind chronic swallowing difficulty. Bei Sha Shen restores the moisture that the esophagus needs to allow food to pass. Chuan Bei Mu dissolves the Phlegm that physically obstructs the passage without adding dryness. Dan Shen and Yu Jin break through the Blood stasis and Qi stagnation that form the deeper structural blockage. Sha Ren Ke awakens the Stomach's natural downward-moving function, while Chu Tou Kang is a traditional specific herb for opening the diaphragm to food. The formula is particularly suited to the early and middle stages of this condition where fluids are beginning to diminish but have not yet been severely depleted.

Also commonly used for

Esophagitis

Inflammation of the esophagus with swallowing difficulty

Gastroesophageal Reflux Disease

When presenting with diaphragm obstruction and Qi stagnation pattern

Nausea

Chronic nausea with retching and difficulty keeping food down

Epigastric Fullness And Pain Relieved By Vomiting

Food eaten in the morning vomited in the evening, or vice versa

What This Formula Does

Every TCM formula has a specific set of actions — here's what Qi Ge San does in the body, explained in both everyday and TCM terms

Therapeutic focus

In practical terms, Qi Ge San is primarily used to support these areas of health:

TCM Actions

In TCM terminology, these are the specific therapeutic actions that Qi Ge San performs to restore balance in the body:

How It Addresses the Root Cause

TCM doesn't just suppress symptoms — it aims to resolve the underlying imbalance. Here's how Qi Ge San works at the root level.

Qi Ge San addresses a condition the classical texts call ye ge (噎膈), or dysphagia with obstruction. The core problem, as Cheng Zhongling memorably stated, comes down to "the Stomach duct being dry and withered" (胃脘干槁). This is fundamentally a Dryness condition, not a Dampness condition, which is why he explicitly warned against using standard anti-emetic drying herbs like Ban Xia.

The disease develops through a cycle of emotional constraint and fluid damage. Prolonged emotional stress, especially worry, frustration, or suppressed anger, causes Qi to stagnate. When Qi stagnates in the chest and diaphragm area, it generates Heat over time. This Heat gradually scorches and consumes the body's Fluids and Yin, causing the lining of the esophagus and Stomach to become parched. Meanwhile, the stagnant Qi also impairs the Spleen's ability to transform and transport, leading to the accumulation of Phlegm. This turbid Phlegm, together with the Qi stagnation and fluid depletion, creates a blockage in the chest and diaphragm region. The result is difficulty swallowing, a sensation of obstruction in the throat or chest, belching that temporarily relieves the fullness, dry retching, and eventually the regurgitation of food or phlegmy fluids.

Because the root involves both Dryness (from Fluid and Yin depletion) and obstruction (from Qi stagnation and Phlegm), effective treatment must simultaneously moisten what is dry, open what is blocked, transform what is congealed, and gently move what is stagnant, without adding further drying or draining that would worsen the parched Stomach.

Formula Properties

Every formula has an inherent temperature, taste, and affinity for specific organs — these properties determine how it interacts with the body

Overall Temperature

Slightly Cool

Taste Profile

Predominantly sweet, slightly bitter, and mildly acrid — sweet to nourish and moisten, bitter to descend and transform Phlegm, acrid to open constraint and move stagnant Qi.

Ingredients

8 herbs

The herbs that make up Qi Ge San, organized by their role in the prescription

King — Main ingredient driving the formula
Deputy — Assists and enhances the King
Assistant — Supports or moderates other herbs
Envoy — Directs the formula to its target
King — Main ingredient driving the formula
Bei Sha Shen

Bei Sha Shen

Glehnia roots

Dosage 9g
Temperature Cool
Taste Bitter, Sweet
Organ Affinity Lungs, Stomach

Role in Qi Ge San

Nourishes Stomach Yin and generates fluids to moisten dryness in the esophagus and diaphragm. As the chief herb at the highest dosage, it addresses the core Yin deficiency and dryness that underlie the swallowing obstruction.
Deputies — Assists and enhances the King
Chuan Bei Mu

Chuan Bei Mu

Sichuan Fritillary bulbs

Dosage 4.5g
Temperature Cool
Taste Bitter, Sweet
Organ Affinity Heart, Lungs
Preparation Remove the heart (去心)

Role in Qi Ge San

Transforms Phlegm and disperses nodules without causing dryness. Works together with Bei Sha Shen to moisten the upper and middle Jiao while clearing Phlegm obstruction that contributes to the swallowing difficulty.
Dan Shen

Dan Shen

Red sage roots

Dosage 9g
Temperature Cool
Taste Bitter
Organ Affinity Heart, Liver

Role in Qi Ge San

Invigorates Blood and dispels stasis. When Qi stagnation persists, it often leads to Blood stasis. Dan Shen addresses this deeper level of obstruction to help open the passages in the diaphragm and esophagus.
Assistants — Supports or moderates other herbs
Yu Jin

Yu Jin

Turmeric tubers

Dosage 1.5g
Temperature Cold
Taste Bitter, Pungent
Organ Affinity Heart, Liver, Lungs

Role in Qi Ge San

Moves Qi, resolves depression, and invigorates Blood. Assists in breaking through the Qi stagnation and emotional constraint that often accompany and worsen dysphagia.
Fu Ling

Fu Ling

Poria-cocos mushrooms

Dosage 3g
Temperature Neutral
Taste Sweet
Organ Affinity Heart, Kidneys, Lungs, Spleen

Role in Qi Ge San

Strengthens the Spleen, resolves Dampness, and transforms Phlegm. Supports the middle Jiao to prevent further Phlegm accumulation and gently tonifies without causing stagnation.
Sha Ren

Sha Ren

Amomum fruits

Dosage 1.2g
Temperature Warm
Taste Pungent
Organ Affinity Kidneys, Spleen, Stomach
Preparation Use the husk (壳) only

Role in Qi Ge San

The husk of Sha Ren is used rather than the seed itself because its aromatic Qi-moving properties are gentler and less drying. It arouses the Stomach, regulates Qi, and prevents the moistening herbs from causing further stagnation.
Envoys — Directs the formula to its target
He Ye

He Ye

Lotus leaves

Dosage 2 pieces
Temperature Neutral
Taste Bitter
Organ Affinity Liver, Spleen, Stomach
Preparation Use the stem attachment (蒂)

Role in Qi Ge San

The base of the lotus leaf lifts clear Yang of the Spleen upward. In a formula focused on descending turbid Phlegm and Qi, this ascending action prevents excessive downward-driving and maintains proper Qi dynamics between ascent and descent.
Mi Pi Kang

Mi Pi Kang

Rice bran

Dosage 1.5g
Temperature Warm
Taste Pungent, Sweet
Organ Affinity Stomach, Large Intestine

Role in Qi Ge San

Rice bran (the inner skin of the rice grain) opens the Stomach and directs Qi downward. It is a traditional specific for treating dysphagia and esophageal obstruction, helping food pass smoothly through the digestive tract.

Why This Combination Works

How the herbs in Qi Ge San complement each other

Overall strategy

Qi Ge San addresses dysphagia (ye ge) caused by the interplay of Qi stagnation, Phlegm accumulation, Blood stasis, and dryness of body fluids in the esophagus and diaphragm. The formula uses a combined approach of moistening dryness, moving Qi, transforming Phlegm, and invigorating Blood, while balancing ascending and descending movements within the chest.

King herbs

Bei Sha Shen (Glehnia root) serves as the King herb at the highest dosage. It nourishes Stomach Yin, generates fluids, and moistens the esophageal and diaphragm region. Dryness of fluids is a fundamental factor making swallowing difficult, and Bei Sha Shen addresses this root cause while tonifying without creating further stagnation.

Deputy herbs

Chuan Bei Mu transforms Phlegm and loosens nodules without adding dryness, making it ideal for conditions where Phlegm and fluid depletion coexist. Dan Shen invigorates Blood and disperses stasis, addressing the deeper obstruction that develops when prolonged Qi stagnation causes Blood to congeal. Together with the King herb, these Deputies tackle three of the four pathogenic factors: dryness, Phlegm, and Blood stasis.

Assistant herbs

Yu Jin (restraining assistant) moves Qi and resolves emotional constraint while also assisting Dan Shen in Blood invigoration. Fu Ling (reinforcing assistant) supports the Spleen to control Phlegm production at its source. Sha Ren Ke (reinforcing assistant) uses the aromatic, gentle Qi of the husk to awaken the Stomach and prevent the moistening herbs from becoming cloying. The original commentary notes that the husk is chosen specifically because it is milder and less drying than the seed.

Envoy herbs

He Ye Di (lotus leaf base) raises clear Yang of the Spleen, providing an upward counterbalance in a formula that primarily descends turbid Qi. Chu Tou Kang (rice bran) opens the Stomach and directs Qi downward, serving as a specific guide for esophageal and diaphragm obstruction. Together, these two envoys harmonize the ascending-descending dynamics of the digestive tract.

Notable synergies

Bei Sha Shen and Chuan Bei Mu together moisten dryness and transform Phlegm simultaneously, addressing what would otherwise be contradictory treatment needs. Dan Shen and Yu Jin form a Blood-moving pair that breaks through stasis from both the Blood and Qi levels. He Ye Di ascending and Chu Tou Kang descending create a balanced Qi dynamic that restores the normal passage of food through the diaphragm.

How to Prepare

Traditional preparation instructions for Qi Ge San

Prepare the herbs as a decoction (despite the name 'San' indicating powder, the original text specifies water decoction). Add all ingredients to approximately 400ml of water and bring to a boil, then simmer on low heat for 20-30 minutes. Strain and take warm after meals. The original text states simply: 水煎服 (decoct in water and take). Chuan Bei Mu should have the heart removed before use (去心).

Common Modifications

How practitioners adapt Qi Ge San for specific situations

Added
Ren Shen

6-9g, to strongly tonify Yuan Qi and support Stomach function

When the patient is constitutionally weak or has become debilitated from prolonged inability to eat, Ren Shen is added to supplement Qi and support the Spleen and Stomach. This is the first modification listed in the original text.

Educational content — always consult a qualified healthcare provider or TCM practitioner before using any herbal formula.

Contraindications

Situations where Qi Ge San should not be used or requires extra caution

Avoid

Dysphagia or occlusion caused by Blood Stasis with inability to swallow food and vomiting of blood. This pattern requires Blood-invigorating and Stasis-dispelling formulas rather than Qi Ge San's gentler approach.

Avoid

Yin Deficiency with severe Body Fluid depletion, characterized by a mirror-like tongue with no coating. In this case the fluids are too depleted for this formula's mild moistening to be sufficient, and stronger Yin-nourishing treatment is needed.

Avoid

Qi and Yang Deficiency patterns with marked weight loss, fatigue, and fading spirits. This formula focuses on opening constraint and transforming Phlegm rather than tonifying, and could further deplete a severely deficient patient.

Avoid

Vomiting caused by Dampness or Phlegm-Damp accumulation in the Stomach. Cheng Zhongling explicitly warns that vomiting is a Damp condition requiring drying, whereas dysphagia (ye ge) is a Dryness condition requiring moistening. Using drying formulas like Ban Xia Tang for dysphagia, or moistening formulas for Damp-type vomiting, are both contraindicated.

Caution

Pregnancy. Dan Shen (Salvia root) invigorates Blood and Yu Jin (Curcuma) moves Qi and Blood, both of which carry theoretical risk of stimulating uterine activity.

Special Populations

Important considerations for pregnancy, breastfeeding, and pediatric use

Pregnancy

Use with caution during pregnancy. Dan Shen (Salvia root) invigorates Blood circulation and Yu Jin (Curcuma tuber) strongly moves Qi and Blood. Both herbs carry a theoretical risk of stimulating uterine contractions or promoting unwanted Blood movement. While neither is a potent abortifacient at standard doses, the combination warrants caution. A qualified practitioner should assess the risk-benefit ratio before prescribing this formula to pregnant women. If dysphagia occurs during pregnancy, alternative approaches that avoid Blood-moving herbs should be considered first.

Breastfeeding

No specific contraindications for breastfeeding have been documented for Qi Ge San in classical or modern sources. The formula's herbs are generally mild in nature. Dan Shen and Yu Jin are Blood-moving herbs that could theoretically pass into breast milk in small amounts, but at standard therapeutic doses this is unlikely to cause harm to a nursing infant. Fu Ling and Sha Ren are widely considered safe. Chuan Bei Mu and Sha Shen are gentle and non-toxic. As a general precaution, breastfeeding mothers should consult a qualified practitioner before use, and the infant should be monitored for any changes in feeding or behavior.

Children

Qi Ge San was originally designed for adult patients with dysphagia, a condition that is uncommon in children. Classical texts do not provide specific pediatric dosing guidelines for this formula. If a practitioner determines it is appropriate for an older child or adolescent (for example, with functional swallowing difficulty or globus sensation), doses would typically be reduced to one-third to one-half of the adult dose depending on the child's age and body weight. The formula is mild and does not contain harsh or toxic ingredients, but the underlying condition it treats (ye ge) would require careful diagnosis in a pediatric patient, as the causes of swallowing difficulty in children differ significantly from those in adults.

Drug Interactions

If you are taking pharmaceutical medications, be aware of these potential interactions with Qi Ge San

Dan Shen (Salvia miltiorrhiza): Dan Shen has well-documented anticoagulant and antiplatelet properties. It may potentiate the effects of blood-thinning medications such as warfarin, heparin, aspirin, and other antiplatelet or anticoagulant drugs, increasing the risk of bleeding. Patients on these medications should be closely monitored if Dan Shen-containing formulas are used.

Yu Jin (Curcuma): Curcuma species contain curcuminoids that may affect hepatic drug metabolism via cytochrome P450 enzymes. This could theoretically alter the metabolism of drugs processed through the liver, though clinical significance at standard formula doses is uncertain.

General caution: Because the formula's primary indication overlaps with conditions (esophageal disease, gastric disorders) that are often managed with proton pump inhibitors, H2 blockers, or prokinetic agents in conventional medicine, patients taking these medications concurrently should inform their prescribing practitioner to avoid unexpected interactions or therapeutic conflicts.

Usage Guidance

Practical advice for getting the most out of Qi Ge San

Best time to take

30 minutes before meals, taken warm in small sips to ease passage through the throat and esophagus.

Typical duration

Typically prescribed for 2-4 weeks initially, then reassessed. Chronic dysphagia conditions may require longer courses of several months with periodic formula adjustments.

Dietary advice

Avoid dry, hard, rough, or difficult-to-swallow foods that would further irritate a parched esophagus and Stomach. Fried, spicy, and heavily seasoned foods should be minimized as they generate further Heat and dryness. Alcohol and strong tea are also best avoided. Cold and raw foods should be limited, as they can impair the already weakened Spleen's digestive function. Favor soft, moist, easily digestible foods: congee (rice porridge), soups, steamed vegetables, and pureed foods. Pear, lily bulb (bai he), and lotus root are traditionally recommended for their moistening qualities. Small, frequent meals are preferable to large ones, allowing the Stomach to process food without becoming overwhelmed.

Qi Ge San originates from Yi Xue Xin Wu (《医学心悟》Medical Revelations), Volume 3, by Cheng Guopeng (程国彭) Qīng dynasty, 1732 CE

Classical Texts

Key passages from the classical Chinese medical texts that first described Qi Ge San and its clinical use

Cheng Zhongling (程钟龄), Yi Xue Xin Wu (《医学心悟》), Volume 3, "Dysphagia" chapter:

「古方治噎膈,多以止吐之剂通用,不思吐,湿症也,宜燥。噎膈,燥症也,宜润。」
"Ancient formulas for treating dysphagia commonly use anti-emetic remedies indiscriminately. They fail to consider that vomiting is a Damp condition, which calls for drying, while dysphagia is a Dryness condition, which calls for moistening."
「经云:三阳结谓之隔。结,结热也,热甚则物干。凡噎膈症,不出胃脘干槁四字。」
"The classics say: 'When the three Yang bind, it is called occlusion.' Binding means binding Heat; when Heat is extreme, things dry out. All cases of dysphagia come down to four characters: the Stomach duct is dry and withered."
「启膈散——通噎膈,开关之剂,屡效。」
"Qi Ge San — a formula that opens dysphagia and unblocks the gate, repeatedly effective."
「槁在上脘者,水饮可行,食物难入。槁在下脘者,食虽可入,久而复出。」
"When the withering is in the upper Stomach duct, liquids can pass but food is hard to swallow. When withering is in the lower Stomach duct, food may enter but is later brought back up."

Historical Context

How Qi Ge San evolved over the centuries — its origins, lineage, and place in the broader tradition of Chinese medicine

Qi Ge San was created by Cheng Guopeng (程国彭), better known by his courtesy name Cheng Zhongling (程钟龄), a prominent physician of the Qing Dynasty. He published it in his influential work Yi Xue Xin Wu (《医学心悟》, "Medical Insights"), completed in 1732. Cheng Zhongling is also renowned for systematizing the "Eight Methods of Treatment" (八法) and for creating other widely used formulas such as Zhi Sou San (止嗽散, "Stop Cough Powder") and Xiao Luo Wan (消瘰丸).

The formula represented a significant conceptual advance in treating dysphagia. Before Cheng, many physicians reflexively used drying, anti-emetic formulas (such as Ban Xia-based prescriptions) for all swallowing difficulties and vomiting conditions alike. Cheng's key insight was distinguishing dysphagia as fundamentally a Dryness condition requiring moistening, in direct opposition to the Dampness-type vomiting that requires drying. He wrote pointedly: "The Stomach is already withered; if you further apply drying herbs, will you not simply increase the dryness?" This made Da Ban Xia Tang and Xiao Ban Xia Tang contraindicated in ye ge. His approach of combining gentle Yin-nourishing and Fluid-generating herbs with Qi-moving and Phlegm-transforming agents became a model for later physicians treating esophageal disorders.

In modern clinical practice, Qi Ge San has been widely adapted for conditions including esophageal cancer, gastric cardia cancer, gastroesophageal reflux disease, achalasia, and other functional esophageal disorders. It also sees use in treating plum-pit Qi (梅核气) and certain forms of chest obstruction (胸痹).